Wavelength and Intensity Dependence of Retinal Evoked Responses Using in vivo Optic Nerve Recording

Warren E. Finn, Peter G. LoPresti

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We use a whole-animal model and wavelength-selective optical stimulation to investigate relationships between optical stimulus characteristics and neural signaling. Light-emitting diodes are used to selectively stimulate rod and cone pathways in Rana pipiens. A suction electrode is used to make in vivo measurements of the compound action potential from the optic nerve as the wavelength and intensity of the stimulus is varied. Our results demonstrate that the cone and rod pathways can be separately stimulated and analyzed with our method and, thus, provide a means to model the response of such pathways to more complex stimuli.

Original languageEnglish
Pages (from-to)372-376
Number of pages5
JournalIEEE Transactions on Neural Systems and Rehabilitation Engineering
Issue number4
Publication statusPublished - 1 Dec 2003



  • Compound action potential
  • Frog
  • Optic nerve
  • Retina

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