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Type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors induce antidepressant-like activity in mice by a mechanism involving receptor potentiation but not neurotransmitter reuptake inhibition. Correlation with mTOR intracellular pathway activation

  • Katarzyna M. Targowska-Duda
  • , Barbara Budzynska
  • , Agnieszka Michalak
  • , Artur Wnorowski
  • , Claus J. Loland
  • , Maciej Maj
  • , Dina Manetti
  • , Maria Novella Romanelli
  • , Krzysztof Jozwiak
  • , Grazyna Biala
  • , Hugo R. Arias

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Pharmacology, Toxicology and Pharmaceutical Science