Type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors induce antidepressant-like activity in mice by a mechanism involving receptor potentiation but not neurotransmitter reuptake inhibition. Correlation with mTOR intracellular pathway activation

Katarzyna M. Targowska-Duda, Barbara Budzynska, Agnieszka Michalak, Artur Wnorowski, Claus J. Loland, Maciej Maj, Dina Manetti, Maria Novella Romanelli, Krzysztof Jozwiak, Grazyna Biala, Hugo R. Arias

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Pharmacology, Toxicology and Pharmaceutical Science