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Topology of ligand binding sites on the nicotinic acetylcholine receptor
Hugo R. Arias
Research output
:
Contribution to journal
›
Review article
›
peer-review
139
Scopus citations
Overview
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Dive into the research topics of 'Topology of ligand binding sites on the nicotinic acetylcholine receptor'. Together they form a unique fingerprint.
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Keyphrases
Binding Site
100%
Nicotinic Acetylcholine Receptor (nAChR)
100%
Ligand Binding Site
100%
Non-competitive Inhibitor
83%
Competitive Antagonist
58%
Acetylcholine Receptor (AChR)
50%
High-affinity Binding Site
25%
Neurotransmitters
25%
Lipid Transfer Protein
25%
Protein-protein Interface
25%
Quinacrine
25%
Lumen
16%
5-hydroxytryptamine
16%
Acetylcholine
16%
Pharmacological Activities
16%
Non-theal
16%
Open Channel
16%
Ligand-binding Domain
16%
Local Anesthetics
16%
High Concentration
8%
Glutamate
8%
High Affinity
8%
Physiological Function
8%
Aspartate
8%
Transmembrane
8%
Membrane Depolarization
8%
Low Affinity
8%
Progesterone
8%
Surface Membrane
8%
Eserine
8%
Testosterone
8%
Negatively Charged
8%
Neurotoxin
8%
Cysteine
8%
Chlorpromazine
8%
Ligand Binding
8%
Evidence Support
8%
Cation Channel
8%
Membrane Surface
8%
Structural Modification
8%
Receptor Subunits
8%
Transmembrane Domain
8%
Conformational Change
8%
Extracellular Domain
8%
Well-differentiated
8%
Blocking Mechanism
8%
Molecular Interactions
8%
Phencyclidine
8%
Acetylcholinesterase Inhibitors (AChEI)
8%
Allosteric Mechanism
8%
Valine
8%
α-bungarotoxin
8%
Co-agonist
8%
Channel Opening
8%
Ion Flux
8%
Agonist Trigger
8%
Agonist Binding
8%
Lipid Domains
8%
Annular Lipids
8%
Lipid Membrane
8%
Channel Blockage
8%
Ethidium
8%
Low-affinity Binding Sites
8%
Vestibule
8%
Neuropeptide Substance P
8%
Cembranoids
8%
Inhibitor Binding Site
8%
Cation Permeation
8%
Complementary Components
8%
Three-loop
8%
Contact Point
8%
Conotoxin
8%
Curare
8%
D-tubocurarine
8%
Chemical Signals
8%
Simple Mechanisms
8%
Extracellular Region
8%
Aromatic Residues
8%
Relative Shift
8%
Neuroscience
Binding Site
100%
Nicotinic Acetylcholine Receptor
100%
Ligand Binding
100%
Agonist
66%
Competitive Inhibition
55%
Cholinergic Receptor
33%
Receptor
22%
Neurotransmitter
16%
Mepacrine
16%
Serotonin
11%
Acetylcholine
11%
Progesterone
5%
Neurotoxin
5%
Cholinergic
5%
Serine
5%
Substance P
5%
Neuropeptide
5%
Cation Channel
5%
Receptor Subunit
5%
Glucocorticoid
5%
Physostigmine
5%
Phencyclidine
5%
Valine
5%
Membrane Lipid
5%
Membrane Depolarization
5%
Lipid Membrane
5%
Bungarotoxin
5%
Chlorpromazine
5%
Cembranoid
5%
Vestibule of the Ear
5%
Acetylcholinesterase Inhibitor
5%
Conotoxin
5%
Tubocurarine Chloride
5%
Cysteine
5%
Glutamates
5%
Cation Transport
5%
Ion Current
5%
Curare
5%
Pharmacology, Toxicology and Pharmaceutical Science
Binding Site
100%
Nicotinic Receptor
100%
Competitive Inhibitor
55%
Competitive Antagonist
38%
Cholinergic Receptor
33%
Receptor
22%
Neurotransmitter
16%
Mepacrine
16%
Acetylcholine
11%
Serotonin
11%
Drug Action
11%
Local Anesthetic Agent
11%
Membrane Lipid
5%
Neurotoxin
5%
Physostigmine
5%
Progesterone
5%
Cysteine
5%
Chlorpromazine
5%
Substance P
5%
Glucocorticoid
5%
Neuropeptide
5%
Cholinergic Receptor Stimulating Agent
5%
Receptor Subunit
5%
Cholinesterase Inhibitor
5%
Valine
5%
Bungarotoxin
5%
Agonist-Antagonist
5%
Serine
5%
Phencyclidine
5%
Cation Channel
5%
Ethidium
5%
Methyltriphenylphosphonium
5%
Cembranoid
5%
Conotoxin
5%
Arrow Poison
5%
Glutamic Acid Derivative
5%
Tubocurarine Chloride
5%
Biochemistry, Genetics and Molecular Biology
Glucocorticoid
5%