TY - JOUR
T1 - Spin the Abstracts of Systematic Reviews and Meta-Analyses Regarding the Treatment of Ménière’s Disease
AU - Heigle, Benjamin
AU - Kee, Micah
AU - Ottwell, Ryan
AU - Arthur, Wade
AU - Brame, Lacy
AU - Wright, Drew N.
AU - Hartwell, Micah
AU - Khojasteh, Jam
AU - Vassar, Matt
N1 - Funding Information:
The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: “Dr. Vassar reports receipt of funding from the National Institute on Drug Abuse, the National Institute on Alcohol Abuse and Alcoholism, the US Office of Research Integrity, Oklahoma Center for Advancement of Science and Technology, and internal grants from Oklahoma State University Center for Health Sciences—all outside of the present work.”
Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Development of this study and its protocol was funded by the Oklahoma State University Center for Health Sciences Presidential Mentor-Mentee Research Fellowship Grant.
Publisher Copyright:
© The Author(s) 2021.
PY - 2021/11
Y1 - 2021/11
N2 - Objectives: To identify, quantify, and characterize the presence of spin—specific strategies leading to misrepresentation of study results—in the abstracts of systematic reviews and meta-analyses of Ménière’s disease treatment. Methods: Using a cross-sectional design, we searched MEDLINE and Embase on May 28, 2020, for systematic reviews and meta-analyses focused on Ménière’s disease treatment. Returned searches were screened, and data were extracted in a masked, duplicate fashion. Results: Our sample included 36 systematic reviews and meta-analyses. Of the 36 included studies, 22 (61.1%) abstracts contained spin while 14 (38.9%) did not. The most common spin types were selective reporting of benefit (10/36, 27.8%) or harm (8/36, 22.2%). Other types of spin occurred when findings were extrapolated to the global improvement of the disease (5/36, 13.9%), beneficial effects were reported with high risk of bias in primary studies (3/36, 8.3%), and when beneficial effects were extrapolated to an entire class of interventions (1/36, 2.8%). No instances of other spin types occurred. Abstracts containing spin were substantively associated with studies of critically low methodological quality compared with studies with low and moderate quality. No studies had a methodological rating of high quality. No associations were observed between spin and intervention types, journal recommendation of adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses, or funding. We found a negative correlation (r = −.31) between abstract word limit and presence of spin. Conclusions: Our study highlights that spin in the abstracts of systematic reviews of Ménière’s disease is common, and it further enhances the discussion surrounding spin in abstracts of scientific research. Spin in an abstract does not discredit a study’s findings; however, its occurrence should be eliminated.
AB - Objectives: To identify, quantify, and characterize the presence of spin—specific strategies leading to misrepresentation of study results—in the abstracts of systematic reviews and meta-analyses of Ménière’s disease treatment. Methods: Using a cross-sectional design, we searched MEDLINE and Embase on May 28, 2020, for systematic reviews and meta-analyses focused on Ménière’s disease treatment. Returned searches were screened, and data were extracted in a masked, duplicate fashion. Results: Our sample included 36 systematic reviews and meta-analyses. Of the 36 included studies, 22 (61.1%) abstracts contained spin while 14 (38.9%) did not. The most common spin types were selective reporting of benefit (10/36, 27.8%) or harm (8/36, 22.2%). Other types of spin occurred when findings were extrapolated to the global improvement of the disease (5/36, 13.9%), beneficial effects were reported with high risk of bias in primary studies (3/36, 8.3%), and when beneficial effects were extrapolated to an entire class of interventions (1/36, 2.8%). No instances of other spin types occurred. Abstracts containing spin were substantively associated with studies of critically low methodological quality compared with studies with low and moderate quality. No studies had a methodological rating of high quality. No associations were observed between spin and intervention types, journal recommendation of adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses, or funding. We found a negative correlation (r = −.31) between abstract word limit and presence of spin. Conclusions: Our study highlights that spin in the abstracts of systematic reviews of Ménière’s disease is common, and it further enhances the discussion surrounding spin in abstracts of scientific research. Spin in an abstract does not discredit a study’s findings; however, its occurrence should be eliminated.
KW - Ménière’s disease
KW - evidence-based medicine
KW - vestibular diseases
UR - http://www.scopus.com/inward/record.url?scp=85102738702&partnerID=8YFLogxK
U2 - 10.1177/00034894211000493
DO - 10.1177/00034894211000493
M3 - Article
C2 - 33730925
AN - SCOPUS:85102738702
SN - 0003-4894
VL - 130
SP - 1268
EP - 1275
JO - Annals of Otology, Rhinology and Laryngology
JF - Annals of Otology, Rhinology and Laryngology
IS - 11
ER -