Abstract
Background: Individuals with heart failure (HF) exhibit comorbid impairments in both sleep and cognitive performance. Sleep quality has been associated with impaired cognitive performance in HF patients, but reports are inconsistent. In this study, we examined associations between sleep quality, daytime sleepiness, and cognitive function in HF. Methods and results: Participants were 267 (age = 69.1 ± 9.3) mostly Caucasian (74.9%), male (59.6%) stable HF patients recruited from outpatient settings. This cross-sectional study was a secondary analysis of a prospective observational study. Cognitive function domains assessed included: global cognitive function, attention, memory, and executive function. Sleep quality and daytime sleepiness were assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Epworth Sleepiness Scale (ESS), respectively. Separate multiple hierarchical linear regressions were conducted to determine associations between cognitive function and sleep quality and daytime sleepiness, after controlling for sex, New York Heart Association (NYHA) class, education, depressive symptoms, and medical comorbidities. Cognitive function was not associated with sleep quality or daytime sleepiness after alpha inflation corrections were applied. Conclusions: Cognitive function in HF is not associated with sleep quality or daytime sleepiness; other factors may exert greater influence on cognitive performance.
| Original language | English |
|---|---|
| Pages (from-to) | 100-106 |
| Number of pages | 7 |
| Journal | Journal of Psychosomatic Research |
| Volume | 113 |
| DOIs | |
| State | Published - 1 Oct 2018 |
| Externally published | Yes |
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Keywords
- Cognition
- Daytime sleepiness
- Heart failure
- Neuropsychological tests
- Sleep quality
Cite this
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Sleep quality and daytime sleepiness are not associated with cognition in heart failure. / Walter, Fawn A.; Ede, David; Hawkins, Misty A.W.; Dolansky, Mary A.; Gunstad, John; Josephson, Richard; Moore, Shirley M.; Hughes, Joel W.
In: Journal of Psychosomatic Research, Vol. 113, 01.10.2018, p. 100-106.Research output: Contribution to journal › Article
TY - JOUR
T1 - Sleep quality and daytime sleepiness are not associated with cognition in heart failure
AU - Walter, Fawn A.
AU - Ede, David
AU - Hawkins, Misty A.W.
AU - Dolansky, Mary A.
AU - Gunstad, John
AU - Josephson, Richard
AU - Moore, Shirley M.
AU - Hughes, Joel W.
PY - 2018/10/1
Y1 - 2018/10/1
N2 - Background: Individuals with heart failure (HF) exhibit comorbid impairments in both sleep and cognitive performance. Sleep quality has been associated with impaired cognitive performance in HF patients, but reports are inconsistent. In this study, we examined associations between sleep quality, daytime sleepiness, and cognitive function in HF. Methods and results: Participants were 267 (age = 69.1 ± 9.3) mostly Caucasian (74.9%), male (59.6%) stable HF patients recruited from outpatient settings. This cross-sectional study was a secondary analysis of a prospective observational study. Cognitive function domains assessed included: global cognitive function, attention, memory, and executive function. Sleep quality and daytime sleepiness were assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Epworth Sleepiness Scale (ESS), respectively. Separate multiple hierarchical linear regressions were conducted to determine associations between cognitive function and sleep quality and daytime sleepiness, after controlling for sex, New York Heart Association (NYHA) class, education, depressive symptoms, and medical comorbidities. Cognitive function was not associated with sleep quality or daytime sleepiness after alpha inflation corrections were applied. Conclusions: Cognitive function in HF is not associated with sleep quality or daytime sleepiness; other factors may exert greater influence on cognitive performance.
AB - Background: Individuals with heart failure (HF) exhibit comorbid impairments in both sleep and cognitive performance. Sleep quality has been associated with impaired cognitive performance in HF patients, but reports are inconsistent. In this study, we examined associations between sleep quality, daytime sleepiness, and cognitive function in HF. Methods and results: Participants were 267 (age = 69.1 ± 9.3) mostly Caucasian (74.9%), male (59.6%) stable HF patients recruited from outpatient settings. This cross-sectional study was a secondary analysis of a prospective observational study. Cognitive function domains assessed included: global cognitive function, attention, memory, and executive function. Sleep quality and daytime sleepiness were assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Epworth Sleepiness Scale (ESS), respectively. Separate multiple hierarchical linear regressions were conducted to determine associations between cognitive function and sleep quality and daytime sleepiness, after controlling for sex, New York Heart Association (NYHA) class, education, depressive symptoms, and medical comorbidities. Cognitive function was not associated with sleep quality or daytime sleepiness after alpha inflation corrections were applied. Conclusions: Cognitive function in HF is not associated with sleep quality or daytime sleepiness; other factors may exert greater influence on cognitive performance.
KW - Cognition
KW - Daytime sleepiness
KW - Heart failure
KW - Neuropsychological tests
KW - Sleep quality
UR - http://www.scopus.com/inward/record.url?scp=85051775597&partnerID=8YFLogxK
U2 - 10.1016/j.jpsychores.2018.08.003
DO - 10.1016/j.jpsychores.2018.08.003
M3 - Article
AN - SCOPUS:85051775597
VL - 113
SP - 100
EP - 106
JO - Journal of Psychosomatic Research
JF - Journal of Psychosomatic Research
SN - 0022-3999
ER -