Regulation of flagellar length in Chlamydomonas

Nedra Wilson, Janaki Kannan Iyer, Julie A. Buchheim, William Meek

Research output: Contribution to journalReview article

35 Citations (Scopus)

Abstract

Chlamydomonas reinhardtii has two apically localized flagella that are maintained at an equal and appropriate length. Assembly and maintenance of flagella requires a microtubule-based transport system known as intraflagellar transport (IFT). During IFT, proteins destined for incorporation into or removal from a flagellum are carried along doublet microtubules via IFT particles. Regulation of IFT activity therefore is pivotal in determining the length of a flagellum. Reviewed is our current understanding of the role of IFT and signal transduction pathways in the regulation of flagellar length.

Original languageEnglish
Pages (from-to)494-501
Number of pages8
JournalSeminars in Cell and Developmental Biology
Volume19
Issue number6
DOIs
StatePublished - 1 Jan 2008

Fingerprint

Chlamydomonas
Flagella
Microtubules
Chlamydomonas reinhardtii
Signal Transduction
Maintenance
Proteins

Keywords

  • Chlamydomonas
  • Cilia
  • Flagellar length
  • Intraflagellar transport
  • Signal transduction

Cite this

Wilson, Nedra ; Iyer, Janaki Kannan ; Buchheim, Julie A. ; Meek, William. / Regulation of flagellar length in Chlamydomonas. In: Seminars in Cell and Developmental Biology. 2008 ; Vol. 19, No. 6. pp. 494-501.
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Regulation of flagellar length in Chlamydomonas. / Wilson, Nedra; Iyer, Janaki Kannan; Buchheim, Julie A.; Meek, William.

In: Seminars in Cell and Developmental Biology, Vol. 19, No. 6, 01.01.2008, p. 494-501.

Research output: Contribution to journalReview article

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