Regulation of flagellar length in Chlamydomonas

Nedra Wilson, Janaki Kannan Iyer, Julie A. Buchheim, William Meek

Research output: Contribution to journalReview articlepeer-review

43 Scopus citations


Chlamydomonas reinhardtii has two apically localized flagella that are maintained at an equal and appropriate length. Assembly and maintenance of flagella requires a microtubule-based transport system known as intraflagellar transport (IFT). During IFT, proteins destined for incorporation into or removal from a flagellum are carried along doublet microtubules via IFT particles. Regulation of IFT activity therefore is pivotal in determining the length of a flagellum. Reviewed is our current understanding of the role of IFT and signal transduction pathways in the regulation of flagellar length.

Original languageEnglish
Pages (from-to)494-501
Number of pages8
JournalSeminars in Cell and Developmental Biology
Issue number6
StatePublished - Dec 2008


  • Chlamydomonas
  • Cilia
  • Flagellar length
  • Intraflagellar transport
  • Signal transduction


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