Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder

Keyphrases

• Major Depressive Disorder 100%
• Kynurenic Acid 100%
• Quinolinic Acid 100%
• Depressed Patients 50%
• Healthy Controls 33%
• DSM-IV-TR 33%
• Metabolic Pathway 33%
• Unmedicated 33%
• Kynurenine 33%
• Kynurenine Metabolites 33%
• Group Differences 16%
• Inverse Correlation 16%
• Remission 16%
• Serum Concentration 16%
• Anhedonia 16%
• As(III) 16%
• Low-grade Inflammation 16%
• Depressive Episode 16%
• 3-hydroxykynurenine 16%
• Ultra-performance Liquid Chromatography Coupled to Tandem Mass Spectrometry 16%
• Number of Depressive Episodes 16%
• Remitted Patients 16%
• Kynurenine Metabolism 16%

Neuroscience

• Major Depressive Disorder 100%
• Kynurenic Acid 100%
• Quinolinic Acid 100%
• Kynurenine 83%
• Metabolic Pathway 50%
• Depression 33%
• Mass Spectrometry 16%
• Anhedonia 16%
• 3-Hydroxykynurenine 16%