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Quinoline is used as a solvent, preservative, flavoring agent in medicine, a component of some fungicides, and a colorant in dyes and paints. Chemically, quinoline displays low solubility in cold water but higher solubility in hot water and organic solvents. The ability of quinoline to move through the ecosystem contaminating multiple areas, is a concern, but certain microorganisms have adapted to degrade quinoline reducing the risk of major quinoline contamination in areas surrounding processing plants. In addition, quinoline does exhibit photosensitivity and the relative instability of quinoline in the environment results in its rapid degradation. Quinoline, which is released into the air, can also undergo photolysis. Acute exposure toxicity to quinoline is characterized by irritation of the airways, the gastrointestinal system, and the eyes. Long-term exposure can result in tumor development, with the liver displaying sensitivity to the in vivo effects of quinoline.

Original languageEnglish
Title of host publicationEncyclopedia of Toxicology, Fourth Edition
Subtitle of host publicationVolume 1-9
ISBN (Electronic)9780128243152
StatePublished - 1 Jan 2023


  • Carcinogen
  • Coal tar
  • Colorant
  • Fungicide
  • Niacin
  • Plasticizer
  • Solvent


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