Pseudothrombotic Microangiopathy and Vitamin B12 Deficiency in Pernicious Anemia

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Vitamin B12 deficiency may present as pseudothrombotic microangiopathy. Pseudothrombotic microangiopathy is anemia, thrombocytopenia, and schistocytosis caused by vitamin B12 deficiency. Pseudothrombotic microangiopathy may be mistaken for microangiopathic hemolytic anemia, confounding appropriate treatment. Evaluation of lactate dehydrogenase, reticulocyte count, bilirubin, and platelet count are most helpful in differentiating pseudothrombotic microangiopathy from a true microangiopathic hemolytic anemia. A case of pseudothrombotic microangiopathy due to severe vitamin B12 deficiency is presented.

Original languageEnglish
Pages (from-to)346-347
Number of pages2
JournalBaylor University Medical Center Proceedings
Issue number3
StatePublished - 1 Jul 2017


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