Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign

Creticus Marak; Achuta Kumar Guddati; Adrita Ashraf; James Smith; Prashant Kaushik

doi:10.7326/aimcc.2022.0508

Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign

Creticus Marak, Achuta Kumar Guddati, Adrita Ashraf, James Smith, Prashant Kaushik

Research output: Contribution to journal › Article › peer-review

Abstract

The most common cancer in men is prostate cancer. The Cheerio sign is the computed tomography finding of multiple pulmonary nodules with central lucency resembling the ring-shaped Cheerio breakfast cereal. Unlike bone metastasis, pulmonary involvement is less common. The Cheerio sign has malignant and benign etiologies. Thyroid transcription factor-1 (TTF-1) stain is commonly used in the diagnosis of primary lung cancer. TTF-1 positivity in cancers of prostate origin is rare, with only case reports and small case series available in the literature. Metastatic prostate cancer presenting with a Cheerio sign has not been reported in the literature.

Original language	English
Article number	e220508
Journal	Annals of Internal Medicine Clinical Cases
Volume	1
Issue number	9
DOIs	https://doi.org/10.7326/aimcc.2022.0508
State	Published - Nov 2022
Externally published	Yes

Keywords

Adenocarcinoma
Bone
Immunohistochemistry
Lung and intrathoracic tumors
Lungs
Metastasis
Metastatic tumors
Prostate cancer
Small cell lung cancer
Thorax

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10.7326/aimcc.2022.0508

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title = "Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign",

abstract = "The most common cancer in men is prostate cancer. The Cheerio sign is the computed tomography finding of multiple pulmonary nodules with central lucency resembling the ring-shaped Cheerio breakfast cereal. Unlike bone metastasis, pulmonary involvement is less common. The Cheerio sign has malignant and benign etiologies. Thyroid transcription factor-1 (TTF-1) stain is commonly used in the diagnosis of primary lung cancer. TTF-1 positivity in cancers of prostate origin is rare, with only case reports and small case series available in the literature. Metastatic prostate cancer presenting with a Cheerio sign has not been reported in the literature.",

keywords = "Adenocarcinoma, Bone, Immunohistochemistry, Lung and intrathoracic tumors, Lungs, Metastasis, Metastatic tumors, Prostate cancer, Small cell lung cancer, Thorax",

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doi = "10.7326/aimcc.2022.0508",

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T1 - Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign

AU - Marak, Creticus

AU - Guddati, Achuta Kumar

AU - Ashraf, Adrita

AU - Smith, James

AU - Kaushik, Prashant

PY - 2022/11

Y1 - 2022/11

N2 - The most common cancer in men is prostate cancer. The Cheerio sign is the computed tomography finding of multiple pulmonary nodules with central lucency resembling the ring-shaped Cheerio breakfast cereal. Unlike bone metastasis, pulmonary involvement is less common. The Cheerio sign has malignant and benign etiologies. Thyroid transcription factor-1 (TTF-1) stain is commonly used in the diagnosis of primary lung cancer. TTF-1 positivity in cancers of prostate origin is rare, with only case reports and small case series available in the literature. Metastatic prostate cancer presenting with a Cheerio sign has not been reported in the literature.

AB - The most common cancer in men is prostate cancer. The Cheerio sign is the computed tomography finding of multiple pulmonary nodules with central lucency resembling the ring-shaped Cheerio breakfast cereal. Unlike bone metastasis, pulmonary involvement is less common. The Cheerio sign has malignant and benign etiologies. Thyroid transcription factor-1 (TTF-1) stain is commonly used in the diagnosis of primary lung cancer. TTF-1 positivity in cancers of prostate origin is rare, with only case reports and small case series available in the literature. Metastatic prostate cancer presenting with a Cheerio sign has not been reported in the literature.

KW - Adenocarcinoma

KW - Bone

KW - Immunohistochemistry

KW - Lung and intrathoracic tumors

KW - Lungs

KW - Metastasis

KW - Metastatic tumors

KW - Prostate cancer

KW - Small cell lung cancer

KW - Thorax

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Prostate Adenocarcinoma With Atypical Immunohistochemistry Presenting With a Cheerio Sign

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