Prevalence and predictors of anemia in a population-based study of octogenarians and centenarians in Georgia

Alyson Haslam, Dorothy B. Hausman, Mary Ann Johnson, Adam Davey, Leonard W. Poon, Robert H. Allen, Sally P. Stabler

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Background. Anemia has been associated with increased physical and financial costs and occurs more frequently in older individuals. Therefore, the primary objectives of this study were to examine the prevalence and possible predictors of anemia in the very old. Methods. Hemoglobin was used to identify those with anemia in a group of centenarians and near centenarians (98+, n = 185) and octogenarians (n = 69), who were recruited as part of the population-based multidisciplinary Georgia Centenarian Study. Blood markers, including ferritin, vitamin B12, red blood cell folate, methylmalonic acid, creatinine, and C-reactive protein, demographic variables, and medication and/or supplement usage were used to determine possible predictors of anemia. Results. The prevalence of anemia was 26.2% in octogenarians and 52.1% in centenarians. Low serum albumin (<3.6 g/dL) and decreased estimated glomerular filtration rate (<45 mL/min/m 2) were predictors of anemia in centenarians. Conclusions. Anemia is a major health issue, particularly as people age. Because of the high prevalence of anemia in older individuals, awareness of the predictors associated with anemia becomes increasingly important so as to reduce the negative consequences associated with it and allow for the identification of steps that can be taken to correct anemia, including managing chronic disease.

Original languageEnglish
Pages (from-to)100-106
Number of pages7
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume67 A
Issue number1
StatePublished - 1 Jan 2012
Externally publishedYes


  • Anemia
  • Centenarians
  • Renal function


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