Possible drug candidates for Alzheimer's disease deduced from studying their binding interactions with α7 nicotinic acetylcholine receptor

Keyphrases

• Alzheimer's Disease 100%
• Nicotinic Acetylcholine Receptor (nAChR) 100%
• Binding Interaction 100%
• Drug Candidates 100%
• Open3D 75%
• Cognitive Deficits 25%
• Partial Agonist 25%
• Attentional Deficits 25%
• Molecular Dynamics Simulation 25%
• DMXBA 25%
• Hydrogen Bonding Interaction 25%
• Structural Information 25%
• Alzheimer's Disease Treatment 25%
• Similarity Search 25%
• Flexible Alignment 25%
• Cys-loop Ligand-gated Ion Channels 25%
• Template Molecule 25%
• Docking Studies 25%
• Hydrophobic-hydrophilic Interactions 25%
• Gx-50 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Alzheimer's Disease 100%
• Nicotinic Receptor 100%
• Combination Therapy 25%
• Partial Agonist 25%
• Cognitive Defect 25%
• Hydrogen Bond 25%
• Ligand Gated Ion Channel 25%

Biochemistry, Genetics and Molecular Biology

• Nicotinic Acetylcholine Receptor 100%
• DNA Template 50%
• Agonist 50%
• Dynamics 25%
• Hydrogen Bond 25%
• Chemical Phenomena 25%
• Ligand-Gated Ion Channel 25%