Photo-nano immunotherapy for metastatic breast cancer using synergistic single-walled carbon nanotubes and glycated chitosan

Feifan Zhou, Aamr Hasanjee, Austin Doughty, Connor West, Hong Liu, Wei R. Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

In our previous work, we constructed a multifunctional nano system, using single-walled carbon nanotube (SWNT) and glycated chitosan (GC), which can synergize photothermal and immunological effects. To further confirm the therapy efficacy, with a metastatic mouse mammary tumor model (4T1), we investigate the therapy effects and immune response induced by SWNT-GC, under laser irradiation. Laser+SWNT-GC treatment not only suppressed the prime tumor, but also induced antitumor immune response. It could be developed into a promising treatment modality for the metastatic breast cancer.

Original languageEnglish
Title of host publicationBiophotonics and Immune Responses X
EditorsWei R. Chen
PublisherSPIE
ISBN (Electronic)9781628414141
DOIs
StatePublished - 2015
Externally publishedYes
EventBiophotonics and Immune Responses X - San Francisco, United States
Duration: 9 Feb 201510 Feb 2015

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9324
ISSN (Print)1605-7422

Conference

ConferenceBiophotonics and Immune Responses X
CountryUnited States
CitySan Francisco
Period9/02/1510/02/15

Keywords

  • Breast metastatic cancer
  • Laser
  • SWNT-GC

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    Zhou, F., Hasanjee, A., Doughty, A., West, C., Liu, H., & Chen, W. R. (2015). Photo-nano immunotherapy for metastatic breast cancer using synergistic single-walled carbon nanotubes and glycated chitosan. In W. R. Chen (Ed.), Biophotonics and Immune Responses X [93240L-1] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9324). SPIE. https://doi.org/10.1117/12.2079378