Obsessive-compulsive disorder: Identification, neurobiology, and treatment

Jackie L. Neel, Vivian M. Stevens, Joan E. Stewart

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Obsessive-compulsive disorder (OCD) is a common psychiatric disorder. It may go unrecognized, however, as many patients are embarrassed by their symptoms and are thus reluctant to report them. Recent research findings on OCD point to neurologic dysfunction in the circuitry of the orbitofrontal cortex and basal ganglia. The advent of the use of serotonin reuptake inhibitors (SRIs) as well as behavioral therapy has greatly improved treatment outcomes for patients with OCD. Given the likelihood that these patients are encountered in primary care consultations, physicians have the opportunity to play a crucial role in the early identification and proper treatment of OCD.

Original languageEnglish
Pages (from-to)81-86
Number of pages6
JournalJournal of the American Osteopathic Association
Issue number2
StatePublished - 2002


  • Basal ganglia
  • Behavioral therapy
  • DSM-IV
  • Diagnostic and Statistical Manual of Mental Disorders
  • Obsessive-compulsive disorder
  • Orbitofrontal cortex
  • Serotonin reuptake inhibitor


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