Newly diagnosed white man with HIV-associated lupus-like nephropathy

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Although HIV-associated nephropathy (HIVAN) is the most common form of glomerulopathy found in HIV-infected patients, other lesions have been reported. Lupus-like glomerulonephritis is a lesion that presents with diffuse proliferative immune-complex trapping with lupus-like features instead of the usual focal segmental collapsing of the glomeruli seen in HIVAN. We present a case report of a newly diagnosed HIV-positive white man who presented with dyspnea, lower-extremity swelling, and overt proteinuria. Although initially it was presumed he had a congestive heart failure, a kidney biopsy was performed that demonstrated an HIV-associated diffuse proliferative immune-complex trapping glomerulopathy with lupus-like features. This article reviews the differences between HIVAN and lupus-like glomerulonephritis.

Original languageEnglish
Pages (from-to)213-217
Number of pages5
JournalInfectious Diseases in Clinical Practice
Issue number3
StatePublished - May 2011


  • HIV-associated nephropathy
  • lupus-like nephritis
  • renal disease


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