Abstract
The expression of c-fos, a marker of neuronal activation, was examined in the gracile nucleus (GN) and nucleus of the solitary tract (NTS) after social interactions, including mating, between male and female prairie voles. In GN, mating, but not non-sexual interactions, induced similar significant increases in c-fos immunoreactivity in both males and females. The increased immunoreactivity was concentrated in medial and dorsal GN suggesting that expression was driven by stimulation of reproductive organs. In contrast, in NTS, mating-induced increases in c-fos expression occurred only in males. These results suggest that both GN and NTS comprise different functional components of mating circuitry and may contribute to pair bonding in monogamous voles.
| Original language | English |
|---|---|
| Pages (from-to) | 115-118 |
| Number of pages | 4 |
| Journal | Neuroscience Letters |
| Volume | 341 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1 May 2003 |
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Keywords
- Gracile
- Microtus
- Nucleus of the solitary tract
- Pair bonding
- Sensory
- Social
- c-fos
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Neuronal activation in the caudal brainstem associated with mating by voles. / Curtis, Tom; Berkley, Karen J.; Wang, Zuo Xin.
In: Neuroscience Letters, Vol. 341, No. 2, 01.05.2003, p. 115-118.Research output: Contribution to journal › Article
TY - JOUR
T1 - Neuronal activation in the caudal brainstem associated with mating by voles
AU - Curtis, Tom
AU - Berkley, Karen J.
AU - Wang, Zuo Xin
PY - 2003/5/1
Y1 - 2003/5/1
N2 - The expression of c-fos, a marker of neuronal activation, was examined in the gracile nucleus (GN) and nucleus of the solitary tract (NTS) after social interactions, including mating, between male and female prairie voles. In GN, mating, but not non-sexual interactions, induced similar significant increases in c-fos immunoreactivity in both males and females. The increased immunoreactivity was concentrated in medial and dorsal GN suggesting that expression was driven by stimulation of reproductive organs. In contrast, in NTS, mating-induced increases in c-fos expression occurred only in males. These results suggest that both GN and NTS comprise different functional components of mating circuitry and may contribute to pair bonding in monogamous voles.
AB - The expression of c-fos, a marker of neuronal activation, was examined in the gracile nucleus (GN) and nucleus of the solitary tract (NTS) after social interactions, including mating, between male and female prairie voles. In GN, mating, but not non-sexual interactions, induced similar significant increases in c-fos immunoreactivity in both males and females. The increased immunoreactivity was concentrated in medial and dorsal GN suggesting that expression was driven by stimulation of reproductive organs. In contrast, in NTS, mating-induced increases in c-fos expression occurred only in males. These results suggest that both GN and NTS comprise different functional components of mating circuitry and may contribute to pair bonding in monogamous voles.
KW - Gracile
KW - Microtus
KW - Nucleus of the solitary tract
KW - Pair bonding
KW - Sensory
KW - Social
KW - c-fos
UR - http://www.scopus.com/inward/record.url?scp=0037402776&partnerID=8YFLogxK
U2 - 10.1016/S0304-3940(03)00175-7
DO - 10.1016/S0304-3940(03)00175-7
M3 - Article
C2 - 12686379
AN - SCOPUS:0037402776
VL - 341
SP - 115
EP - 118
JO - Neuroscience Letters
JF - Neuroscience Letters
SN - 0304-3940
IS - 2
ER -