Neuromodulation in postherpetic neuralgia: Case reports and review of the literature

Svetlana Kurklinsky, Scott C. Palmer, Mack J. Arroliga, Salim M. Ghazi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective. Postherpetic neuralgia (PHN) is common in the United States. Current treatment options for PHN are fairly limited. Spinal cord stimulation (SCS) and peripheral nerve stimulation (PNS) are considered mostly experimental and still rarely performed in patients with PHN. Design. Two case reports and a review of the literature. Setting. Tertiary academic medical center. Methods. 1) Pubmed, Ovid, and EBMR databases were searched for all reports that had the following key words: postherpetic neuralgia, spinal cord stimulation, and peripheral nerve stimulation. 2) A retrospective chart review was performed for all the patients that underwent PNS for PHN at Mayo Clinic Florida (MCF). Results. There were 20 original reports that described 309 patients with PHN who were treated with SCS. Sixteen reports had a permanent implantation of SCS, with a total of 255 patients, out of which 120 had long-term pain relief. There were six reports of subcutaneous PNS for PHN (in a thoracic area). Four reports provided data on success rates where all five patients received complete pain relief. In our practice, two patients underwent subcutaneous PNS for PHN (in the thoracic area) with good pain relief for 10 months and 2.5 years, respectively. Conclusions. Based on our review of the literature and the two cases at MCF, subcutaneous PNS seems to be a promising intervention in the treatment of PHN.

Original languageEnglish
Pages (from-to)1237-1244
Number of pages8
JournalPain Medicine (United States)
Volume19
Issue number6
DOIs
StatePublished - 1 Jun 2018

Fingerprint

Postherpetic Neuralgia
Peripheral Nerves
Spinal Cord Stimulation
Pain
Thorax
PubMed
Databases

Keywords

  • Chronic pain
  • Peripheral nerve stimulation
  • PHN
  • PNS
  • Postherpetic neuralgia
  • SCS
  • Spinal cord stimulation

Cite this

Kurklinsky, Svetlana ; Palmer, Scott C. ; Arroliga, Mack J. ; Ghazi, Salim M. / Neuromodulation in postherpetic neuralgia : Case reports and review of the literature. In: Pain Medicine (United States). 2018 ; Vol. 19, No. 6. pp. 1237-1244.
@article{46b7ff820d4143c9a7d464c20fc7a515,
title = "Neuromodulation in postherpetic neuralgia: Case reports and review of the literature",
abstract = "Objective. Postherpetic neuralgia (PHN) is common in the United States. Current treatment options for PHN are fairly limited. Spinal cord stimulation (SCS) and peripheral nerve stimulation (PNS) are considered mostly experimental and still rarely performed in patients with PHN. Design. Two case reports and a review of the literature. Setting. Tertiary academic medical center. Methods. 1) Pubmed, Ovid, and EBMR databases were searched for all reports that had the following key words: postherpetic neuralgia, spinal cord stimulation, and peripheral nerve stimulation. 2) A retrospective chart review was performed for all the patients that underwent PNS for PHN at Mayo Clinic Florida (MCF). Results. There were 20 original reports that described 309 patients with PHN who were treated with SCS. Sixteen reports had a permanent implantation of SCS, with a total of 255 patients, out of which 120 had long-term pain relief. There were six reports of subcutaneous PNS for PHN (in a thoracic area). Four reports provided data on success rates where all five patients received complete pain relief. In our practice, two patients underwent subcutaneous PNS for PHN (in the thoracic area) with good pain relief for 10 months and 2.5 years, respectively. Conclusions. Based on our review of the literature and the two cases at MCF, subcutaneous PNS seems to be a promising intervention in the treatment of PHN.",
keywords = "Chronic pain, Peripheral nerve stimulation, PHN, PNS, Postherpetic neuralgia, SCS, Spinal cord stimulation",
author = "Svetlana Kurklinsky and Palmer, {Scott C.} and Arroliga, {Mack J.} and Ghazi, {Salim M.}",
year = "2018",
month = "6",
day = "1",
doi = "10.1093/pm/pnx175",
language = "English",
volume = "19",
pages = "1237--1244",
journal = "Pain Medicine (United States)",
issn = "1526-2375",
number = "6",

}

Neuromodulation in postherpetic neuralgia : Case reports and review of the literature. / Kurklinsky, Svetlana; Palmer, Scott C.; Arroliga, Mack J.; Ghazi, Salim M.

In: Pain Medicine (United States), Vol. 19, No. 6, 01.06.2018, p. 1237-1244.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Neuromodulation in postherpetic neuralgia

T2 - Case reports and review of the literature

AU - Kurklinsky, Svetlana

AU - Palmer, Scott C.

AU - Arroliga, Mack J.

AU - Ghazi, Salim M.

PY - 2018/6/1

Y1 - 2018/6/1

N2 - Objective. Postherpetic neuralgia (PHN) is common in the United States. Current treatment options for PHN are fairly limited. Spinal cord stimulation (SCS) and peripheral nerve stimulation (PNS) are considered mostly experimental and still rarely performed in patients with PHN. Design. Two case reports and a review of the literature. Setting. Tertiary academic medical center. Methods. 1) Pubmed, Ovid, and EBMR databases were searched for all reports that had the following key words: postherpetic neuralgia, spinal cord stimulation, and peripheral nerve stimulation. 2) A retrospective chart review was performed for all the patients that underwent PNS for PHN at Mayo Clinic Florida (MCF). Results. There were 20 original reports that described 309 patients with PHN who were treated with SCS. Sixteen reports had a permanent implantation of SCS, with a total of 255 patients, out of which 120 had long-term pain relief. There were six reports of subcutaneous PNS for PHN (in a thoracic area). Four reports provided data on success rates where all five patients received complete pain relief. In our practice, two patients underwent subcutaneous PNS for PHN (in the thoracic area) with good pain relief for 10 months and 2.5 years, respectively. Conclusions. Based on our review of the literature and the two cases at MCF, subcutaneous PNS seems to be a promising intervention in the treatment of PHN.

AB - Objective. Postherpetic neuralgia (PHN) is common in the United States. Current treatment options for PHN are fairly limited. Spinal cord stimulation (SCS) and peripheral nerve stimulation (PNS) are considered mostly experimental and still rarely performed in patients with PHN. Design. Two case reports and a review of the literature. Setting. Tertiary academic medical center. Methods. 1) Pubmed, Ovid, and EBMR databases were searched for all reports that had the following key words: postherpetic neuralgia, spinal cord stimulation, and peripheral nerve stimulation. 2) A retrospective chart review was performed for all the patients that underwent PNS for PHN at Mayo Clinic Florida (MCF). Results. There were 20 original reports that described 309 patients with PHN who were treated with SCS. Sixteen reports had a permanent implantation of SCS, with a total of 255 patients, out of which 120 had long-term pain relief. There were six reports of subcutaneous PNS for PHN (in a thoracic area). Four reports provided data on success rates where all five patients received complete pain relief. In our practice, two patients underwent subcutaneous PNS for PHN (in the thoracic area) with good pain relief for 10 months and 2.5 years, respectively. Conclusions. Based on our review of the literature and the two cases at MCF, subcutaneous PNS seems to be a promising intervention in the treatment of PHN.

KW - Chronic pain

KW - Peripheral nerve stimulation

KW - PHN

KW - PNS

KW - Postherpetic neuralgia

KW - SCS

KW - Spinal cord stimulation

UR - http://www.scopus.com/inward/record.url?scp=85050606534&partnerID=8YFLogxK

U2 - 10.1093/pm/pnx175

DO - 10.1093/pm/pnx175

M3 - Article

C2 - 29016994

AN - SCOPUS:85050606534

VL - 19

SP - 1237

EP - 1244

JO - Pain Medicine (United States)

JF - Pain Medicine (United States)

SN - 1526-2375

IS - 6

ER -