Microvilli and cell-cell fusion during fertilization

Nedra F. Wilson, William J. Snell

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


A number of fundamental biological processes, ranging from fertilization and embryonic development to viral infection, depend upon a complex interplay between cells that results in the fusion of their plasma membranes. Surprisingly, the cellular and molecular mechanisms underlying cell-cell fusion remain largely unknown. Here, the authors discuss evidence suggesting that microvilli play a central role in fusion of many cells and present features of these actin-filled, a cell-surface protrusions that might make them particularly well suited as cell-fusion organelles.

Original languageEnglish
Pages (from-to)93-96
Number of pages4
JournalTrends in Cell Biology
Issue number3
StatePublished - Mar 1998


Dive into the research topics of 'Microvilli and cell-cell fusion during fertilization'. Together they form a unique fingerprint.

Cite this