Microvilli and cell-cell fusion during fertilization

Nedra Wilson, William J. Snell

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

A number of fundamental biological processes, ranging from fertilization and embryonic development to viral infection, depend upon a complex interplay between cells that results in the fusion of their plasma membranes. Surprisingly, the cellular and molecular mechanisms underlying cell-cell fusion remain largely unknown. Here, the authors discuss evidence suggesting that microvilli play a central role in fusion of many cells and present features of these actin-filled, a cell-surface protrusions that might make them particularly well suited as cell-fusion organelles.

Original languageEnglish
Pages (from-to)93-96
Number of pages4
JournalTrends in Cell Biology
Volume8
Issue number3
DOIs
StatePublished - 1 Jan 1998

Fingerprint

Cell Fusion
Microvilli
Fertilization
Cell Surface Extensions
Biological Phenomena
Virus Diseases
Organelles
Embryonic Development
Actins
Cell Membrane

Cite this

Wilson, Nedra ; Snell, William J. / Microvilli and cell-cell fusion during fertilization. In: Trends in Cell Biology. 1998 ; Vol. 8, No. 3. pp. 93-96.
@article{f6f7ae773447463d9dcec4b5f6e00652,
title = "Microvilli and cell-cell fusion during fertilization",
abstract = "A number of fundamental biological processes, ranging from fertilization and embryonic development to viral infection, depend upon a complex interplay between cells that results in the fusion of their plasma membranes. Surprisingly, the cellular and molecular mechanisms underlying cell-cell fusion remain largely unknown. Here, the authors discuss evidence suggesting that microvilli play a central role in fusion of many cells and present features of these actin-filled, a cell-surface protrusions that might make them particularly well suited as cell-fusion organelles.",
author = "Nedra Wilson and Snell, {William J.}",
year = "1998",
month = "1",
day = "1",
doi = "10.1016/S0962-8924(98)01234-3",
language = "English",
volume = "8",
pages = "93--96",
journal = "Trends in Cell Biology",
issn = "0962-8924",
publisher = "Elsevier Ltd",
number = "3",

}

Microvilli and cell-cell fusion during fertilization. / Wilson, Nedra; Snell, William J.

In: Trends in Cell Biology, Vol. 8, No. 3, 01.01.1998, p. 93-96.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Microvilli and cell-cell fusion during fertilization

AU - Wilson, Nedra

AU - Snell, William J.

PY - 1998/1/1

Y1 - 1998/1/1

N2 - A number of fundamental biological processes, ranging from fertilization and embryonic development to viral infection, depend upon a complex interplay between cells that results in the fusion of their plasma membranes. Surprisingly, the cellular and molecular mechanisms underlying cell-cell fusion remain largely unknown. Here, the authors discuss evidence suggesting that microvilli play a central role in fusion of many cells and present features of these actin-filled, a cell-surface protrusions that might make them particularly well suited as cell-fusion organelles.

AB - A number of fundamental biological processes, ranging from fertilization and embryonic development to viral infection, depend upon a complex interplay between cells that results in the fusion of their plasma membranes. Surprisingly, the cellular and molecular mechanisms underlying cell-cell fusion remain largely unknown. Here, the authors discuss evidence suggesting that microvilli play a central role in fusion of many cells and present features of these actin-filled, a cell-surface protrusions that might make them particularly well suited as cell-fusion organelles.

UR - http://www.scopus.com/inward/record.url?scp=0032030639&partnerID=8YFLogxK

U2 - 10.1016/S0962-8924(98)01234-3

DO - 10.1016/S0962-8924(98)01234-3

M3 - Article

C2 - 9695816

AN - SCOPUS:0032030639

VL - 8

SP - 93

EP - 96

JO - Trends in Cell Biology

JF - Trends in Cell Biology

SN - 0962-8924

IS - 3

ER -