Mesenteric vein thrombosis caused by secondary polycythaemia from AndroGel

Heather Katz, Eugene Popov, Natasha Bray, Barry Berman

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Mesenteric vein thrombosis is a rare but potentially lethal cause of abdominal pain. It is usually caused by prothrombotic states that can either be hereditary or acquired. Testosterone supplementation causes an acquired prothrombotic state by promoting erythropoeisis thus causing a secondary polycythaemia. We report a case of a 59-year-old man with a history of chronic obstructive pulmonary disease (COPD) stage III, who presented with abdominal pain. Evaluation revealed an elevated haemoglobin and haematocrit, a superior mesenteric vein thrombosis on CT and a negative Janus kinase 2 mutation. The patient is currently being treated with 6 months of anticoagulation with rivaroxiban. Although a well-known side effect of testosterone is thrombosis, the present case is used to document in the literature the first case of mesenteric vein thrombosis due to secondary polycythaemia from Androgel in the setting of COPD.

Original languageEnglish
JournalBMJ Case Reports
Volume2014
DOIs
StatePublished - 21 Oct 2014

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Mesenteric Veins
Polycythemia
Testosterone
Thrombosis
Chronic Obstructive Pulmonary Disease
Abdominal Pain
Janus Kinase 2
Hematocrit
Hemoglobins
Mutation

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Katz, Heather ; Popov, Eugene ; Bray, Natasha ; Berman, Barry. / Mesenteric vein thrombosis caused by secondary polycythaemia from AndroGel. In: BMJ Case Reports. 2014 ; Vol. 2014.
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Mesenteric vein thrombosis caused by secondary polycythaemia from AndroGel. / Katz, Heather; Popov, Eugene; Bray, Natasha; Berman, Barry.

In: BMJ Case Reports, Vol. 2014, 21.10.2014.

Research output: Contribution to journalArticle

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