Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13

L. Deforche, E. Roose, A. Vandenbulcke, N. Vandeputte, H. B. Feys, T. A. Springer, L. Z. Mi, J. Muia, J. E. Sadler, K. Soejima, H. Rottensteiner, H. Deckmyn, S. F. De Meyer, K. Vanhoorelbeke