Lethality of sortase depletion in Actinomyces oris caused by excessive membrane accumulation of a surface glycoprotein

Keyphrases

• Acac 60%
• Actinomyces Oris 100%
• Bacterial Fitness 20%
• Bacterial Growth 20%
• Bacterial Pathogenesis 20%
• Cell Viability 20%
• Cell Wall 40%
• Cell Wall Proteins 20%
• Cell-based 20%
• Cysteine Transpeptidase 20%
• Genetic Suppressor 20%
• Glyco 20%
• Glycosylated Forms 20%
• Glycosylation 20%
• Glycosylation Pathway 20%
• Gram-positive Bacteria 20%
• Gram-positive Pathogens 40%
• Housekeeping 40%
• Lethality 100%
• LytR-CpsA-Psr 40%
• Membrane Accumulation 100%
• Membrane Localization Domain 20%
• Novel Phenomena 20%
• Overexpressing 20%
• Overexpression 20%
• Protein Substrate 20%
• Sortase A 100%
• SrtA 100%
• Surface Glycoprotein 100%
• Surface Proteins 20%
• Tn5 mutagenesis 20%
• Transposon Insertion 20%
• Virulence 20%

Biochemistry, Genetics and Molecular Biology

• Actinomyces 100%
• Bacterial Growth 20%
• Cell Surface Protein 20%
• Cell Viability 20%
• Cysteine 20%
• Gamma-Glutamyl Transpeptidase 20%
• Genetics 40%
• Glycoprotein 100%
• Glycosylation 40%
• Gram Positive Bacterium 20%
• Infectious Agent 40%
• Sortase 100%
• Transposable Element 20%
• Transposon Mutagenesis 20%

Immunology and Microbiology

• Actinomyces 100%
• Bacterial Growth 20%
• Bacterial Pathogenesis 20%
• Cell Viability 20%
• Cell Wall 60%
• Glycoprotein 100%
• Glycosylation 40%
• Gram-Positive Bacteria 20%
• Infectious Agent 40%
• Mutagenesis 20%
• Sortase 100%
• Transposon 40%