Isolated diastolic hypertension associated risk factors among Chinese in Anhui Province, China

Yanchun Wang, Fengjun Xing, Rongjuan Liu, Li Liu, Yu Zhu, Yufeng Wen, Wenjie Sun, Ziwei Song

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Objective: To explore potential risk factors of isolated diastolic hypertension (IDH) among young and middle-aged Chinese. Methods: A community-based cross-sectional study was conducted among 338 subjects, aged 25 years and above, using random sampling technique. There were 68 cases of IDH, 46 cases of isolated systolic hypertension (ISH), 89 cases of systolic and diastolic hypertension (SDH), and 135 of subjects with normal blood pressure. Cases and controls were matched on sex by frequency matching. Demographic characteristics, blood pressure and other relevant information were collected. Results: Compared with controls, patients with IDH and ISH had significant higher level of triglyceride, high density lipoprotein, blood glucose and body mass index (BMI) (p < 0.05); while patients with SDH had significantly higher level of total cholesterol, triglyceride, glucose and BMI (p < 0.05). Linear mixed effects model showed that drinking tea, family history of hypertension (FHH), higher blood glucose, triglyceride and low density lipoprotein were related with elevated diastolic blood pressure (DBP) (p < 0.01); HFH, blood glucose, creatinine and BMI have positive effect on systolic blood pressure (SBP) (p < 0.05). Conclusions: Drinking tea, FHH, high levels of triglyceride, high density lipoprotein, blood glucose and BMI are associated with IDH among young and middle-aged Chinese.

Original languageEnglish
Pages (from-to)4395-4405
Number of pages11
JournalInternational Journal of Environmental Research and Public Health
Volume12
Issue number4
DOIs
StatePublished - Apr 2015
Externally publishedYes

Keywords

  • Case-control study
  • Isolated diastolic hypertension
  • Linear mixed model

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