Is oral therapy an option for endocarditis associated with injection drug use?

Infective endocarditis is commonly treated with prolonged courses of intravenous antibiotics and may invoke a high cost burden to institutions and patients. Oral therapy may be an option in a specific subset of patients with endocarditis. We report the successful treatment of a patient with endocarditis with an oral regimen and a review of the literature available to support this option.