Interpeduncular fossa lipoma: A novel cause of oculomotor nerve palsy in childhood

Jay R. Malone, Amanda Bogie, Cathryn Crittenden-Byers

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Oculomotor nerve palsy is a rare finding in children and, when reported, is most frequently either congenital or acquired from postnatal trauma, infection, aneurysm, or migraine. Intracranial lipomas also represent an uncommon finding in children, and although their development is not completely understood, they are now thought to be congenital in nature. Here, we describe the case of a 23-month-old boy presenting to the emergency department with left-sided, complete, pupil-involving oculomotor nerve palsy. On magnetic resonance imaging, he was found to have an intracranial lipoma of the left interpeduncular fossa. The patient had gradual and spontaneous improvement of symptoms, with complete resolution reported at the 4-month follow-up visit. However, a second magnetic resonance image at 6 months revealed that the lipoma did not change in size. To our knowledge, intracranial lipomas have been previously reported as a possible cause of partial oculomotor nerve palsy in only one adult and have never been reported in a child. In addition, we did not find any reports of intracranial lipomas as a cause of complete, pupil-involving oculomotor palsy, although they are known to cause other cranial nerve pathology. We conclude that intracranial lipomas, although rare, should be considered in the differential diagnosis for oculomotor nerve palsy in children. Further investigation is needed to determine the true incidence of this association.

Original languageEnglish
Pages (from-to)160-162
Number of pages3
JournalPediatric Emergency Care
Volume28
Issue number2
DOIs
StatePublished - 1 Feb 2012

Fingerprint

Oculomotor Nerve Diseases
Lipoma
Pupil
Cranial Nerves
Migraine Disorders
Paralysis
Aneurysm
Hospital Emergency Service
Differential Diagnosis
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Pathology
Incidence
Wounds and Injuries
Infection

Keywords

  • infant
  • intracranial neoplasms
  • lipoma
  • oculomotor nerve diseases

Cite this

@article{466bc5c83559420386d8a18c4311fd76,
title = "Interpeduncular fossa lipoma: A novel cause of oculomotor nerve palsy in childhood",
abstract = "Oculomotor nerve palsy is a rare finding in children and, when reported, is most frequently either congenital or acquired from postnatal trauma, infection, aneurysm, or migraine. Intracranial lipomas also represent an uncommon finding in children, and although their development is not completely understood, they are now thought to be congenital in nature. Here, we describe the case of a 23-month-old boy presenting to the emergency department with left-sided, complete, pupil-involving oculomotor nerve palsy. On magnetic resonance imaging, he was found to have an intracranial lipoma of the left interpeduncular fossa. The patient had gradual and spontaneous improvement of symptoms, with complete resolution reported at the 4-month follow-up visit. However, a second magnetic resonance image at 6 months revealed that the lipoma did not change in size. To our knowledge, intracranial lipomas have been previously reported as a possible cause of partial oculomotor nerve palsy in only one adult and have never been reported in a child. In addition, we did not find any reports of intracranial lipomas as a cause of complete, pupil-involving oculomotor palsy, although they are known to cause other cranial nerve pathology. We conclude that intracranial lipomas, although rare, should be considered in the differential diagnosis for oculomotor nerve palsy in children. Further investigation is needed to determine the true incidence of this association.",
keywords = "infant, intracranial neoplasms, lipoma, oculomotor nerve diseases",
author = "Malone, {Jay R.} and Amanda Bogie and Cathryn Crittenden-Byers",
year = "2012",
month = "2",
day = "1",
doi = "10.1097/PEC.0b013e3182447716",
language = "English",
volume = "28",
pages = "160--162",
journal = "Pediatric Emergency Care",
issn = "0749-5161",
number = "2",

}

Interpeduncular fossa lipoma : A novel cause of oculomotor nerve palsy in childhood. / Malone, Jay R.; Bogie, Amanda; Crittenden-Byers, Cathryn.

In: Pediatric Emergency Care, Vol. 28, No. 2, 01.02.2012, p. 160-162.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Interpeduncular fossa lipoma

T2 - A novel cause of oculomotor nerve palsy in childhood

AU - Malone, Jay R.

AU - Bogie, Amanda

AU - Crittenden-Byers, Cathryn

PY - 2012/2/1

Y1 - 2012/2/1

N2 - Oculomotor nerve palsy is a rare finding in children and, when reported, is most frequently either congenital or acquired from postnatal trauma, infection, aneurysm, or migraine. Intracranial lipomas also represent an uncommon finding in children, and although their development is not completely understood, they are now thought to be congenital in nature. Here, we describe the case of a 23-month-old boy presenting to the emergency department with left-sided, complete, pupil-involving oculomotor nerve palsy. On magnetic resonance imaging, he was found to have an intracranial lipoma of the left interpeduncular fossa. The patient had gradual and spontaneous improvement of symptoms, with complete resolution reported at the 4-month follow-up visit. However, a second magnetic resonance image at 6 months revealed that the lipoma did not change in size. To our knowledge, intracranial lipomas have been previously reported as a possible cause of partial oculomotor nerve palsy in only one adult and have never been reported in a child. In addition, we did not find any reports of intracranial lipomas as a cause of complete, pupil-involving oculomotor palsy, although they are known to cause other cranial nerve pathology. We conclude that intracranial lipomas, although rare, should be considered in the differential diagnosis for oculomotor nerve palsy in children. Further investigation is needed to determine the true incidence of this association.

AB - Oculomotor nerve palsy is a rare finding in children and, when reported, is most frequently either congenital or acquired from postnatal trauma, infection, aneurysm, or migraine. Intracranial lipomas also represent an uncommon finding in children, and although their development is not completely understood, they are now thought to be congenital in nature. Here, we describe the case of a 23-month-old boy presenting to the emergency department with left-sided, complete, pupil-involving oculomotor nerve palsy. On magnetic resonance imaging, he was found to have an intracranial lipoma of the left interpeduncular fossa. The patient had gradual and spontaneous improvement of symptoms, with complete resolution reported at the 4-month follow-up visit. However, a second magnetic resonance image at 6 months revealed that the lipoma did not change in size. To our knowledge, intracranial lipomas have been previously reported as a possible cause of partial oculomotor nerve palsy in only one adult and have never been reported in a child. In addition, we did not find any reports of intracranial lipomas as a cause of complete, pupil-involving oculomotor palsy, although they are known to cause other cranial nerve pathology. We conclude that intracranial lipomas, although rare, should be considered in the differential diagnosis for oculomotor nerve palsy in children. Further investigation is needed to determine the true incidence of this association.

KW - infant

KW - intracranial neoplasms

KW - lipoma

KW - oculomotor nerve diseases

UR - http://www.scopus.com/inward/record.url?scp=84857161245&partnerID=8YFLogxK

U2 - 10.1097/PEC.0b013e3182447716

DO - 10.1097/PEC.0b013e3182447716

M3 - Article

C2 - 22307184

AN - SCOPUS:84857161245

VL - 28

SP - 160

EP - 162

JO - Pediatric Emergency Care

JF - Pediatric Emergency Care

SN - 0749-5161

IS - 2

ER -