Interoceptive predictions in the brain

Lisa Feldman Barrett, W. Kyle Simmons

Research output: Contribution to journalReview article

435 Scopus citations

Abstract

Intuition suggests that perception follows sensation and therefore bodily feelings originate in the body. However, recent evidence goes against this logic: interoceptive experience may largely reflect limbic predictions about the expected state of the body that are constrained by ascending visceral sensations. In this Opinion article, we introduce the Embodied Predictive Interoception Coding model, which integrates an anatomical model of corticocortical connections with Bayesian active inference principles, to propose that agranular visceromotor cortices contribute to interoception by issuing interoceptive predictions. We then discuss how disruptions in interoceptive predictions could function as a common vulnerability for mental and physical illness.

Original languageEnglish
Pages (from-to)419-429
Number of pages11
JournalNature Reviews Neuroscience
Volume16
Issue number7
DOIs
StatePublished - 22 Jul 2015
Externally publishedYes

Fingerprint Dive into the research topics of 'Interoceptive predictions in the brain'. Together they form a unique fingerprint.

Cite this