Interaction of benzylidene-anabaseine analogues with agonist and allosteric sites on muscle nicotinic acetylcholine receptors

Keyphrases

• Anabaseine 100%
• Allosteric Site 100%
• Muscle Nicotinic Acetylcholine Receptor 100%
• Benzylidene 100%
• Nicotinic Acetylcholine Receptor (nAChR) 61%
• Competitive Antagonist 22%
• Partial Agonist 16%
• Torpedo 16%
• Fetal muscle 16%
• Human Fetus 16%
• Dizocilpine 11%
• 4-hydroxy-2 11%
• High Affinity 5%
• Cyclohexyl 5%
• Mechanism of Action 5%
• Binding Site 5%
• Specific Binding 5%
• Direct Interaction 5%
• Ion Channels 5%
• Blocking Mechanism 5%
• Competition Binding 5%
• Binding Experiment 5%
• Desensitized State 5%
• Phencyclidine 5%
• Co-agonist 5%
• Muscle Type 5%
• Radioligand Binding Assay 5%
• Thienyl 5%
• Channel Blockage 5%
• Primary Metabolites 5%
• Tetracaine 5%
• Direct Channel 5%
• Functional Binding 5%
• Amobarbital 5%
• Non-competitive Inhibition 5%
• Antagonist Activity 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Nicotinic Receptor 100%
• 3 (2,4 Dimethoxybenzylidene)anabaseine 100%
• Competitive Antagonist 50%
• Partial Agonist 37%
• Dizocilpine 25%
• Binding Site 12%
• Radioligand 12%
• Carbon 14 12%
• Ion Channel 12%
• Agonist-Antagonist 12%
• Phencyclidine 12%
• Non-Competitive Inhibition 12%
• Tetracaine 12%
• Amobarbital 12%