Abstract
Introduction/Objectives: Natural Orifice Transluminal Endoscopic Surgery (NOTES), introduced in 2004, involves the utilization of natural orifices to allow access to the peritoneal cavity for endoscopic surgery—which more recently has been used via the vagina (vNOTES). Given the novelty of vNOTES, our primary objective was to assess clinical trials that have been conducted using this technique in the field of OB/GYN.
Methods: We conducted a cross-sectional analysis of the National Library of Medicine’s Clinical Trial Database to assess the current spectrum of vNOTES clinical trials and their characteristics.
Results: We found 21 clinical trials meeting the inclusion criteria—of which only 5 had been completed and only 1 of these reported results. Additionally, only 2 of the trials were registered in the United States.
Conclusions: While there is only 1 trial with reported results via clinicaltrials.gov, this study showed fewer postoperative complications than laparoscopic surgery, such as urinary tract infections. The novelty of the technique requires further investigation as well as practice guidelines for its use. Although there are limited trials on vNOTES, it may be beneficial for patients who are candidates for vaginal hysterectomy.
Methods: We conducted a cross-sectional analysis of the National Library of Medicine’s Clinical Trial Database to assess the current spectrum of vNOTES clinical trials and their characteristics.
Results: We found 21 clinical trials meeting the inclusion criteria—of which only 5 had been completed and only 1 of these reported results. Additionally, only 2 of the trials were registered in the United States.
Conclusions: While there is only 1 trial with reported results via clinicaltrials.gov, this study showed fewer postoperative complications than laparoscopic surgery, such as urinary tract infections. The novelty of the technique requires further investigation as well as practice guidelines for its use. Although there are limited trials on vNOTES, it may be beneficial for patients who are candidates for vaginal hysterectomy.
Original language | American English |
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Pages | 72 |
State | Published - 16 Feb 2024 |
Event | Oklahoma State University Center for Health Sciences Research Week 2024 - Oklahoma State University Center for Health Sciences, Tulsa, United States Duration: 13 Feb 2024 → 17 Feb 2024 https://medicine.okstate.edu/research/research_days.html |
Conference
Conference | Oklahoma State University Center for Health Sciences Research Week 2024 |
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Country/Territory | United States |
City | Tulsa |
Period | 13/02/24 → 17/02/24 |
Internet address |
Keywords
- Natural Orifice Transluminal Endoscopic Surgery,
- vNOTES
- Clinicaltrials.gov
- hysterectomy