Insights into Innovation: Examining vNOTES in OB/GYN via

Vina Nguyen, Natasha Bray, Jameca Price, Micah Hartwell

Research output: Contribution to conferencePosterpeer-review


Introduction/Objectives: Natural Orifice Transluminal Endoscopic Surgery (NOTES), introduced in 2004, involves the utilization of natural orifices to allow access to the peritoneal cavity for endoscopic surgery—which more recently has been used via the vagina (vNOTES). Given the novelty of vNOTES, our primary objective was to assess clinical trials that have been conducted using this technique in the field of OB/GYN.

Methods: We conducted a cross-sectional analysis of the National Library of Medicine’s Clinical Trial Database to assess the current spectrum of vNOTES clinical trials and their characteristics.

Results: We found 21 clinical trials meeting the inclusion criteria—of which only 5 had been completed and only 1 of these reported results. Additionally, only 2 of the trials were registered in the United States.

Conclusions: While there is only 1 trial with reported results via, this study showed fewer postoperative complications than laparoscopic surgery, such as urinary tract infections. The novelty of the technique requires further investigation as well as practice guidelines for its use. Although there are limited trials on vNOTES, it may be beneficial for patients who are candidates for vaginal hysterectomy.
Original languageAmerican English
StatePublished - 16 Feb 2024
Oklahoma State University Center for Health Sciences Research Week 2024
- Oklahoma State University Center for Health Sciences, Tulsa, United States
Duration: 13 Feb 202417 Feb 2024


Oklahoma State University Center for Health Sciences Research Week 2024
Country/TerritoryUnited States
Internet address


  • Natural Orifice Transluminal Endoscopic Surgery,
  • vNOTES
  • hysterectomy


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