Immunization with recombinant TcdB-encapsulated nanocomplex induces protection against Clostridium difficile challenge in a mouse model

Keyphrases

• Mouse Model 100%
• Recombinant 100%
• Immunization 100%
• Clostridioides Difficile 100%
• TcdA 100%
• Nanocomplex 100%
• C.difficile Infection 75%
• Chitosan 50%
• Vaccine Development 50%
• Neutralizing Antibodies 25%
• Health Systems 25%
• Antibody Titer 25%
• Inflammatory Chemokines 25%
• Cytotoxin 25%
• Vaccination 25%
• Receptor-binding Domain 25%
• Medical Costs 25%
• Nanoparticles 25%
• Difficile 25%
• Bacterial Vaccines 25%
• Antigen Delivery System 25%
• Recombinant Protein 25%
• Poly-γ-glutamic Acid (γ-PGA) 25%
• Antibody Response 25%
• Lethal Dose 25%
• Infectious Diarrhea 25%
• Aluminum Hydroxide 25%
• Activity Domains 25%
• Antigen Carrier 25%
• Full Protection 25%
• Toxin Activity 25%
• Viral Vaccines 25%
• Vaccine Design 25%
• Biodegradable Nanoparticles 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Mouse Model 100%
• Peptoclostridium difficile 100%
• Clostridium Difficile Infection 100%
• Nanoparticle 66%
• Vaccine Development 66%
• Chitosan 66%
• Receptor 33%
• Cytokine 33%
• Chemokine 33%
• Cytotoxin 33%
• Adjuvant 33%
• Virus Vaccine 33%
• Neutralizing Antibody 33%
• Polyglutamic Acid 33%
• Bacterial Vaccine 33%
• Aluminum Hydroxide 33%
• Recombinant Protein 33%
• Infectious Diarrhea 33%