Hyperdense Middle Cerebral Artery Sign in the Setting of Acute Cerebral Ischemia: A Case Report

Kaylee Mach; J. Blake Snow; Sean Hayes; Jamison Williams; Samuel Jellison; Donald von Borstel

Hyperdense Middle Cerebral Artery Sign in the Setting of Acute Cerebral Ischemia: A Case Report

Kaylee Mach, J. Blake Snow, Sean Hayes, Jamison Williams, Samuel Jellison, Donald von Borstel

Research output: Contribution to journal › Article › peer-review

Abstract

Non-contrast computed tomography (CT) is the initial imaging modality of choice for acute stroke symptoms.⁵ Other imaging modalities, such as CT angiogram (CTA) and CT perfusion studies, can help confirm ischemic stroke, identify viable tissue, and determine therapeutic intervention.¹ One of the earliest signs of ischemia on non-contrast CT in stroke patients is the hyperdense middle cerebral artery sign (HMCAS).² The HMCAS is suggestive of acute occlusion within the branches of the middle cerebral artery (MCA).³ In this case, a patient presented with delayed-onset neurological symptoms in the presence of the HMCAS. Imaging proved to guide the therapeutic approach and gave insight necessary to reveal arterial involvement and tissue injury. Identification of this HMCAS in patients is valuable as its presence has been directly correlated to poor clinical outcomes when treatment is delayed.⁴

Original language	American English
Article number	219
Number of pages	9
Journal	Oklahoma State Medical Proceedings
Volume	8
Issue number	1
State	Published - 6 May 2024

Access to Document

https://www.okstatemedicalproceedings.com/index.php/OSMP/article/view/219

Cite this

@article{f91b4b30e21c41198c5fac31c5f4ddea,

title = "Hyperdense Middle Cerebral Artery Sign in the Setting of Acute Cerebral Ischemia: A Case Report",

abstract = "Non-contrast computed tomography (CT) is the initial imaging modality of choice for acute stroke symptoms.5 Other imaging modalities, such as CT angiogram (CTA) and CT perfusion studies, can help confirm ischemic stroke, identify viable tissue, and determine therapeutic intervention.1 One of the earliest signs of ischemia on non-contrast CT in stroke patients is the hyperdense middle cerebral artery sign (HMCAS).2 The HMCAS is suggestive of acute occlusion within the branches of the middle cerebral artery (MCA).3 In this case, a patient presented with delayed-onset neurological symptoms in the presence of the HMCAS. Imaging proved to guide the therapeutic approach and gave insight necessary to reveal arterial involvement and tissue injury. Identification of this HMCAS in patients is valuable as its presence has been directly correlated to poor clinical outcomes when treatment is delayed.4",

author = "Kaylee Mach and Snow, {J. Blake} and Sean Hayes and Jamison Williams and Samuel Jellison and {von Borstel}, Donald",

note = "Ethical Statement: Research conducted through OSU-CHS adheres to the 1979 report of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, Ethical Principles and Guidelines for the Protection of Human Subjects of Research (“The Belmont Report”). Case reports are not considered to be human subject research under the purview of the IRB (45 CFR 46.104 Exempt Research 4.ii.). Therefore, this case report did not require review by the OSUMC Ethical Committee for the Protection of Human Subjects.",

year = "2024",

month = may,

day = "6",

language = "American English",

volume = "8",

journal = "Oklahoma State Medical Proceedings",

issn = "2475-8914",

number = "1",

}

TY - JOUR

T1 - Hyperdense Middle Cerebral Artery Sign in the Setting of Acute Cerebral Ischemia: A Case Report

AU - Mach, Kaylee

AU - Snow, J. Blake

AU - Hayes, Sean

AU - Williams, Jamison

AU - Jellison, Samuel

AU - von Borstel, Donald

N1 - Ethical Statement: Research conducted through OSU-CHS adheres to the 1979 report of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, Ethical Principles and Guidelines for the Protection of Human Subjects of Research (“The Belmont Report”). Case reports are not considered to be human subject research under the purview of the IRB (45 CFR 46.104 Exempt Research 4.ii.). Therefore, this case report did not require review by the OSUMC Ethical Committee for the Protection of Human Subjects.

PY - 2024/5/6

Y1 - 2024/5/6

N2 - Non-contrast computed tomography (CT) is the initial imaging modality of choice for acute stroke symptoms.5 Other imaging modalities, such as CT angiogram (CTA) and CT perfusion studies, can help confirm ischemic stroke, identify viable tissue, and determine therapeutic intervention.1 One of the earliest signs of ischemia on non-contrast CT in stroke patients is the hyperdense middle cerebral artery sign (HMCAS).2 The HMCAS is suggestive of acute occlusion within the branches of the middle cerebral artery (MCA).3 In this case, a patient presented with delayed-onset neurological symptoms in the presence of the HMCAS. Imaging proved to guide the therapeutic approach and gave insight necessary to reveal arterial involvement and tissue injury. Identification of this HMCAS in patients is valuable as its presence has been directly correlated to poor clinical outcomes when treatment is delayed.4

AB - Non-contrast computed tomography (CT) is the initial imaging modality of choice for acute stroke symptoms.5 Other imaging modalities, such as CT angiogram (CTA) and CT perfusion studies, can help confirm ischemic stroke, identify viable tissue, and determine therapeutic intervention.1 One of the earliest signs of ischemia on non-contrast CT in stroke patients is the hyperdense middle cerebral artery sign (HMCAS).2 The HMCAS is suggestive of acute occlusion within the branches of the middle cerebral artery (MCA).3 In this case, a patient presented with delayed-onset neurological symptoms in the presence of the HMCAS. Imaging proved to guide the therapeutic approach and gave insight necessary to reveal arterial involvement and tissue injury. Identification of this HMCAS in patients is valuable as its presence has been directly correlated to poor clinical outcomes when treatment is delayed.4

M3 - Article

SN - 2475-8914

VL - 8

JO - Oklahoma State Medical Proceedings

JF - Oklahoma State Medical Proceedings

IS - 1

M1 - 219

ER -

Hyperdense Middle Cerebral Artery Sign in the Setting of Acute Cerebral Ischemia: A Case Report

Abstract

Access to Document

Fingerprint

Cite this