HLA‐linked susceptibility to rheumatoid arthritis in North India

N. K. Mehra, R. Kaul, V. Taneja, T. K. Chaudhuri, B. Jhinghan, A. N. Malaviya

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Nine multiplex RA families of North Indian origin were tissue typed to determine the segregation of parental haplotypes among sibs. The assortment of haplotypes in 18 affected sibs was not random, with seven sib pairs being HLA identical and two haploidentical with the proband (P = 0.0007). HLA‐DR4 occurred in eight out of nine probands (88.8%) and in 11 out of 13 familial RA subjects (84.6%).

Original languageEnglish
Pages (from-to)220-223
Number of pages4
JournalTissue Antigens
Issue number4
StatePublished - Apr 1988


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