HIV-associated primary effusion lymphoma presenting as a paracardial mass

Heather Katz, Cielo Rose, Nina Thakker Rivera, Natasha Bray

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Primary effusion lymphoma (PEL), a rare type of non- Hodgkin's lymphoma, is an AIDS-defining illness and always associated with human herpesvirus 8 (HHV-8). Classic presentations involve the pleural, pericardial or peritoneal cavities. Infrequently, extracavitary solid tumours develop. Treatment of PEL requires chemotherapy and highly active antiretroviral therapy (HAART). We report a case of a 46-year-old man, who presented with right-sided chest pain, dyspnoea and night sweats. Evaluation revealed decreased breath sounds and dullness to percussion on the right side of the chest. Imaging demonstrated a 6.1 cm×6.3 cm right paracardial mass and right-sided pleural effusion. Pleural fluid was HHV-8 positive. The patient was diagnosed with PEL with extracavitary involvement and treated with chemotherapy and concurrent HAART. This case is the first reported case of extracavitary paracardial involvement and adds new insight to the accepted treatment for PEL with extracavitary lesions.

Original languageEnglish
Article number208718
JournalBMJ Case Reports
Volume2015
DOIs
StatePublished - 27 Feb 2015

Fingerprint

Primary Effusion Lymphoma
HIV
Human Herpesvirus 8
Highly Active Antiretroviral Therapy
Percussion
Drug Therapy
Pleural Cavity
Sweat
Pericardium
Peritoneal Cavity
Pleural Effusion
Chest Pain
Dyspnea
Non-Hodgkin's Lymphoma
Acquired Immunodeficiency Syndrome
Thorax
Therapeutics
Neoplasms

Cite this

Katz, Heather ; Rose, Cielo ; Rivera, Nina Thakker ; Bray, Natasha. / HIV-associated primary effusion lymphoma presenting as a paracardial mass. In: BMJ Case Reports. 2015 ; Vol. 2015.
@article{bb15c216d44f48cda755e89aadb707b4,
title = "HIV-associated primary effusion lymphoma presenting as a paracardial mass",
abstract = "Primary effusion lymphoma (PEL), a rare type of non- Hodgkin's lymphoma, is an AIDS-defining illness and always associated with human herpesvirus 8 (HHV-8). Classic presentations involve the pleural, pericardial or peritoneal cavities. Infrequently, extracavitary solid tumours develop. Treatment of PEL requires chemotherapy and highly active antiretroviral therapy (HAART). We report a case of a 46-year-old man, who presented with right-sided chest pain, dyspnoea and night sweats. Evaluation revealed decreased breath sounds and dullness to percussion on the right side of the chest. Imaging demonstrated a 6.1 cm×6.3 cm right paracardial mass and right-sided pleural effusion. Pleural fluid was HHV-8 positive. The patient was diagnosed with PEL with extracavitary involvement and treated with chemotherapy and concurrent HAART. This case is the first reported case of extracavitary paracardial involvement and adds new insight to the accepted treatment for PEL with extracavitary lesions.",
author = "Heather Katz and Cielo Rose and Rivera, {Nina Thakker} and Natasha Bray",
year = "2015",
month = "2",
day = "27",
doi = "10.1136/bcr-2014-208718",
language = "English",
volume = "2015",
journal = "BMJ Case Reports",
issn = "1757-790X",
publisher = "BMJ Publishing Group",

}

HIV-associated primary effusion lymphoma presenting as a paracardial mass. / Katz, Heather; Rose, Cielo; Rivera, Nina Thakker; Bray, Natasha.

In: BMJ Case Reports, Vol. 2015, 208718, 27.02.2015.

Research output: Contribution to journalArticle

TY - JOUR

T1 - HIV-associated primary effusion lymphoma presenting as a paracardial mass

AU - Katz, Heather

AU - Rose, Cielo

AU - Rivera, Nina Thakker

AU - Bray, Natasha

PY - 2015/2/27

Y1 - 2015/2/27

N2 - Primary effusion lymphoma (PEL), a rare type of non- Hodgkin's lymphoma, is an AIDS-defining illness and always associated with human herpesvirus 8 (HHV-8). Classic presentations involve the pleural, pericardial or peritoneal cavities. Infrequently, extracavitary solid tumours develop. Treatment of PEL requires chemotherapy and highly active antiretroviral therapy (HAART). We report a case of a 46-year-old man, who presented with right-sided chest pain, dyspnoea and night sweats. Evaluation revealed decreased breath sounds and dullness to percussion on the right side of the chest. Imaging demonstrated a 6.1 cm×6.3 cm right paracardial mass and right-sided pleural effusion. Pleural fluid was HHV-8 positive. The patient was diagnosed with PEL with extracavitary involvement and treated with chemotherapy and concurrent HAART. This case is the first reported case of extracavitary paracardial involvement and adds new insight to the accepted treatment for PEL with extracavitary lesions.

AB - Primary effusion lymphoma (PEL), a rare type of non- Hodgkin's lymphoma, is an AIDS-defining illness and always associated with human herpesvirus 8 (HHV-8). Classic presentations involve the pleural, pericardial or peritoneal cavities. Infrequently, extracavitary solid tumours develop. Treatment of PEL requires chemotherapy and highly active antiretroviral therapy (HAART). We report a case of a 46-year-old man, who presented with right-sided chest pain, dyspnoea and night sweats. Evaluation revealed decreased breath sounds and dullness to percussion on the right side of the chest. Imaging demonstrated a 6.1 cm×6.3 cm right paracardial mass and right-sided pleural effusion. Pleural fluid was HHV-8 positive. The patient was diagnosed with PEL with extracavitary involvement and treated with chemotherapy and concurrent HAART. This case is the first reported case of extracavitary paracardial involvement and adds new insight to the accepted treatment for PEL with extracavitary lesions.

UR - http://www.scopus.com/inward/record.url?scp=84928922743&partnerID=8YFLogxK

U2 - 10.1136/bcr-2014-208718

DO - 10.1136/bcr-2014-208718

M3 - Article

C2 - 25725030

AN - SCOPUS:84928922743

VL - 2015

JO - BMJ Case Reports

JF - BMJ Case Reports

SN - 1757-790X

M1 - 208718

ER -