Histamine-releasing activity and binding to the FcεRIα human mast cell receptor subunit of mast cell degranulating peptide analogues with alanine substitutions

Medicine & Life Sciences

• mast cell degranulating peptide receptor 100%
• Alanine 41%
• Mast Cells 39%
• Histamine 39%
• Histamine Release 27%
• Peptides 26%
• Proline 9%
• Fluorescence Polarization 6%
• Competitive Binding 5%
• Lysine 4%
• Immunoglobulin E 4%

Chemical Compounds

• Alanine 39%
• Substitution Reaction 25%
• Histamine 25%
• Peptide 23%
• Kd 6%
• Proline Residue 5%
• L-Alanine 5%
• Lysine Residue 5%
• Proline 4%
• Polarization 3%
• Fluorescence 2%