TY - JOUR
T1 - Fos expression in non-catecholaminergic neurons in medullary and pontine nuclei after volume depletion induced by polyethylene glycol
AU - Curtis, Kathleen S.
AU - Krause, Eric G.
AU - Contreras, Robert J.
N1 - Funding Information:
NIH grants from the National Institute on Deafness and Communication Disorders, DC-02641 and DC-04785, supported this research. We thank Dr. Zuoxin Wang for his valuable advice and assistance.
PY - 2002/9/6
Y1 - 2002/9/6
N2 - Fos immunocytochemistry was combined with immunolabeling for dopamine-β-hydroxylase (DBH) to examine neuronal activation in the medulla and pons after administration of polyethelene glycol (PEG), which produces volume depletion without altering arterial blood pressure. Increased Fos immunoreactivity was observed in the area postrema, nucleus of the solitary tract, rostral ventrolateral medulla, lateral parabrachial nucleus, and the dorsomedial pons at the level of the locus coeruleus. Fos immunolabeling in the caudal nucleus of the solitary tract, rostral ventrolateral medulla, and the dorsomedial pons occurred primarily in neurons that did not contain DBH. Thus, PEG activates non-catecholaminergic neurons in medullary and pontine areas associated with cardiovascular and body fluid regulation.
AB - Fos immunocytochemistry was combined with immunolabeling for dopamine-β-hydroxylase (DBH) to examine neuronal activation in the medulla and pons after administration of polyethelene glycol (PEG), which produces volume depletion without altering arterial blood pressure. Increased Fos immunoreactivity was observed in the area postrema, nucleus of the solitary tract, rostral ventrolateral medulla, lateral parabrachial nucleus, and the dorsomedial pons at the level of the locus coeruleus. Fos immunolabeling in the caudal nucleus of the solitary tract, rostral ventrolateral medulla, and the dorsomedial pons occurred primarily in neurons that did not contain DBH. Thus, PEG activates non-catecholaminergic neurons in medullary and pontine areas associated with cardiovascular and body fluid regulation.
KW - Area postrema
KW - Caudal ventrolateral medulla
KW - Lateral parabrachial nucleus
KW - Locus coeruleus
KW - Nucleus tractus solitarius
KW - Rostral ventrolateral medulla
UR - http://www.scopus.com/inward/record.url?scp=0037032102&partnerID=8YFLogxK
U2 - 10.1016/S0006-8993(02)03051-2
DO - 10.1016/S0006-8993(02)03051-2
M3 - Article
C2 - 12383967
AN - SCOPUS:0037032102
SN - 0006-8993
VL - 948
SP - 149
EP - 154
JO - Brain Research
JF - Brain Research
IS - 1-2
ER -