Fiber-optic sensor system for evaluating spatial selectivity of stimulation by a micro-electrode array

Peter G. LoPresti, Warren Finn

Research output: Contribution to journalConference article

Abstract

A fiber optic sensor has been developed for use in vertically positioning micro-electrode arrays in close proximity to the retina of a live subject. Closely spaced optical fibers illuminate and collection reflections from the retinal surface, and the resultant output electronically processed and used to drive an automated positioning circuit. Systematic evaluation of fiber types and separation on both specular and diffuse reflectors is reported, resulting in the choice of multi-mode fibers on 125μm centers for retinal experimentation. In vitro and in vivo evaluations produced quite similar sensor responses, slowly rising to a peak at a height of 300μm and sharply dropping to zero as the surface is approached. The sensor has applications in assessing the spatial selectivity of stimulation of a multi-electrode array versus height, and can be potentially adapted for lateral positioning.

Original languageEnglish
Pages (from-to)2299-2302
Number of pages4
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume5
StatePublished - 1 Dec 1997
EventProceedings of the 1997 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Chicago, IL, USA
Duration: 30 Oct 19972 Nov 1997

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Fiber optic sensors
Electrodes
Multimode fibers
Sensors
Optical fibers
Networks (circuits)
Fibers

Cite this

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abstract = "A fiber optic sensor has been developed for use in vertically positioning micro-electrode arrays in close proximity to the retina of a live subject. Closely spaced optical fibers illuminate and collection reflections from the retinal surface, and the resultant output electronically processed and used to drive an automated positioning circuit. Systematic evaluation of fiber types and separation on both specular and diffuse reflectors is reported, resulting in the choice of multi-mode fibers on 125μm centers for retinal experimentation. In vitro and in vivo evaluations produced quite similar sensor responses, slowly rising to a peak at a height of 300μm and sharply dropping to zero as the surface is approached. The sensor has applications in assessing the spatial selectivity of stimulation of a multi-electrode array versus height, and can be potentially adapted for lateral positioning.",
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AB - A fiber optic sensor has been developed for use in vertically positioning micro-electrode arrays in close proximity to the retina of a live subject. Closely spaced optical fibers illuminate and collection reflections from the retinal surface, and the resultant output electronically processed and used to drive an automated positioning circuit. Systematic evaluation of fiber types and separation on both specular and diffuse reflectors is reported, resulting in the choice of multi-mode fibers on 125μm centers for retinal experimentation. In vitro and in vivo evaluations produced quite similar sensor responses, slowly rising to a peak at a height of 300μm and sharply dropping to zero as the surface is approached. The sensor has applications in assessing the spatial selectivity of stimulation of a multi-electrode array versus height, and can be potentially adapted for lateral positioning.

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