Explosive onset of SLE in white male in capital of Cherokee Nation

Caleb Alexander, Prashant Kaushik

Research output: Contribution to journalArticlepeer-review


Systemic lupus erythematosus (SLE) is a major autoimmune rheumatologic condition that can cause severe life threatening complications. While it afflicts all ages, sexes, races and ethnicities, it overwhelmingly affects more females and non-white males. Due to these demographics, it is important to highlight this case of an explosive onset of SLE in a young, white male from a unique location in the USA. A 19-year old, white male first had symptoms following a change to carnivore diet, increase in exercise and prolonged sun exposure. Over the first few months, a rash that had started on his face and was originally thought to be a sunburn spread across the majority of his body. He then developed ascending joint pains and a loss of appetite. Over the course of about 6 months, he had gone from a relatively healthy, but overweight, teenager to requiring hospitalization for severe body pains and rash, photophobia, hyperacusis, lack of an appetite and nearly 30-percent loss of body weight loss. Since disease identification and receiving treatment, the symptoms have begun improving and he is resuming normal daily activities.
Original languageAmerican English
JournalAmerican Journal of Medical and Clinical Sciences
Issue number1
StatePublished - 2024


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