Evaluation of 'spin' in the abstracts and articles of randomized controlled trials in pain literature and general anesthesia

Jaime W. Thompson, Ross Tanzer, Tate Triska, Jay Thompson, Trevor Bright, Cole Wayant, Matt Vassar

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To evaluate the abstracts and articles of randomized controlled trials (RCTs) in pain literature and general anesthesia for the evidence of spin. Materials & methods: Following a priori protocol, we used a PubMed search for RCTs from a 2-year period. Data extracted using the Boutron spin definition for criteria. Results: A total of 163 articles were identified as RCTs with clear primary and secondary end points. A total of 33 trials were identified with nonsignificant primary end points. An 18/33 were found to have spin (54.5%). The spin was identified in the results, title and conclusion 12/18, 3/18 and 3/18, respectively. Conclusion: Spin was found in 54% of pain RCTs. With sensitive clinical concerns, such as chronic pain, any misrepresentation of validity could prove to have significant clinical consequences.

Original languageEnglish
Pages (from-to)23-28
Number of pages6
JournalPain Management
Volume11
Issue number1
DOIs
StatePublished - Jan 2020

Keywords

  • general anesthesia
  • pain
  • pain management
  • randomized control trials
  • spin

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