Electronic cigarette aerosols suppress cellular antioxidant defenses and induce significant oxidative DNA damage

Agriculture & Biology

• cigarettes 70%
• DNA damage 57%
• electronics 54%
• antioxidant activity 42%
• smoke 29%
• extracts 27%
• reactive oxygen species 10%
• glycosylases 9%
• antioxidants 8%
• nicotine 7%
• genotoxicity 7%
• assays 6%
• carcinogens 6%
• DNA 6%
• toxic substances 6%
• public health 6%
• cell viability 6%
• epithelial cells 5%
• Western blotting 5%
• tobacco 5%
• enzyme-linked immunosorbent assay 5%
• lungs 5%
• reverse transcriptase polymerase chain reaction 5%
• mouth 5%
• neoplasms 4%
• protein synthesis 4%
• methodology 3%
• dosage 3%
• enzymes 2%
• cells 2%

Medicine & Life Sciences

• Electronic Nicotine Delivery Systems 82%
• Aerosols 63%
• DNA Damage 50%
• Antioxidants 43%
• Smoke 24%
• 8-Hydroxy-2'-Deoxyguanosine 16%
• Reactive Oxygen Species 10%
• DNA Glycosylases 9%
• 8-hydroxyguanine 9%
• Nicotine 6%
• Carcinogens 6%
• Tobacco 6%
• Smokers 5%
• Cell Survival 4%
• Epithelial Cells 4%
• Public Health 4%
• Enzyme-Linked Immunosorbent Assay 4%
• Western Blotting 4%
• Polymerase Chain Reaction 3%
• Messenger RNA 3%
• DNA 3%
• Enzymes 3%
• Lung 3%
• Proteins 2%
• Neoplasms 2%

Chemical Compounds

• Electronic Cigarette 100%
• Aerosol 60%
• Antioxidant Agent 44%
• Smoke 29%
• Reactive Oxygen Metabolite 12%
• DNA 8-Oxoguanine 11%
• Nicotine 7%
• Genotoxicity 7%
• Cell Viability 6%
• Protein 2%