Effects of the adjuvant MPL+TDM on tumor challenge in the B16 mouse melanoma model

Joseph A. Price; J. Michael C. McGee; Marion R. Patten; Diane Snyder

doi:10.1016/0192-0561(96)00003-3

Effects of the adjuvant MPL+TDM on tumor challenge in the B16 mouse melanoma model

Joseph A. Price, J. Michael C. McGee, Marion R. Patten, Diane Snyder

Pathology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Mice were injected three times at 2 week intervals with the adjuvant MPL+TDM or phosphate-buffered saline. Two weeks after the last injection, all mice were challenged subcutaneously with a tumorgenic dose of B16 tumor and observed for 40 days. The adjuvant hastened the time at which tumors appeared (P = 0.02).

Original language	English
Pages (from-to)	163-165
Number of pages	3
Journal	International Journal of Immunopharmacology
Volume	18
Issue number	2
DOIs	https://doi.org/10.1016/0192-0561(96)00003-3
State	Published - 1996

Keywords

Adjuvant
B16
Immunotherapy
MPL+TDM
Tumor
Vaccine

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10.1016/0192-0561(96)00003-3

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title = "Effects of the adjuvant MPL+TDM on tumor challenge in the B16 mouse melanoma model",

abstract = "Mice were injected three times at 2 week intervals with the adjuvant MPL+TDM or phosphate-buffered saline. Two weeks after the last injection, all mice were challenged subcutaneously with a tumorgenic dose of B16 tumor and observed for 40 days. The adjuvant hastened the time at which tumors appeared (P = 0.02).",

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author = "Price, {Joseph A.} and McGee, {J. Michael C.} and Patten, {Marion R.} and Diane Snyder",

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AU - Price, Joseph A.

AU - McGee, J. Michael C.

AU - Patten, Marion R.

AU - Snyder, Diane

PY - 1996

Y1 - 1996

N2 - Mice were injected three times at 2 week intervals with the adjuvant MPL+TDM or phosphate-buffered saline. Two weeks after the last injection, all mice were challenged subcutaneously with a tumorgenic dose of B16 tumor and observed for 40 days. The adjuvant hastened the time at which tumors appeared (P = 0.02).

AB - Mice were injected three times at 2 week intervals with the adjuvant MPL+TDM or phosphate-buffered saline. Two weeks after the last injection, all mice were challenged subcutaneously with a tumorgenic dose of B16 tumor and observed for 40 days. The adjuvant hastened the time at which tumors appeared (P = 0.02).

KW - Adjuvant

KW - B16

KW - Immunotherapy

KW - MPL+TDM

KW - Tumor

KW - Vaccine

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Effects of the adjuvant MPL+TDM on tumor challenge in the B16 mouse melanoma model

Abstract

Keywords

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