@inproceedings{515abf2173e24064824ea98dd4d5e416,
title = "Effects of cyclophosphamide on laser immunotherapy for the treatment of metastatic cancer",
abstract = "Laser immunotherapy (LIT) is an innovative cancer modality that uses laser irradiation and immunological stimulation to treat late-stage, metastatic cancers. The current mode of operation in LIT is through interstitial laser irradiation. Although LIT is still in development, recent clinical trials have shown that it can be used to successfully treat patients with late-stage breast cancer and melanoma. Cyclophosphamide is a chemotherapy drug that suppresses regulatory T cells when used in low doses. In this study tumor-bearing rats were treated with LIT using an 805-nm laser with a power of 2.0 W and low-dose cyclophosphamide. Glycated chitosan was used as an immunological stimulant. The goal was to observe the effects of different doses of cyclophosphamide in addition to LIT on the survival of the tumor-bearing rats.",
keywords = "Cyclophosphamide, Glycated chitosan, Immunological stimulant, Interstitial laser irradiation, Metastatic cancer, Rat tumor",
author = "Bahavar, {Cody F.} and Acquaviva, {Joseph T.} and Sheyla Rabei and Allie Sikes and Nordquist, {Robert E.} and Tomas Hode and Hong Liu and Chen, {Wei R.}",
year = "2014",
month = jan,
day = "1",
doi = "10.1117/12.2040954",
language = "English",
isbn = "9780819498571",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
booktitle = "Biophotonics and Immune Responses IX",
note = "Biophotonics and Immune Responses IX ; Conference date: 03-02-2014 Through 03-02-2014",
}