Abstract
Clinical Scenario: Iron deficiency without anemia is a common disorder found in many individuals. Patient may experience fatigue, lack of energy, and mood changes. One treatment option for this condition is supplementation, which can be done via diet, intravenously (IV), or orally. IV supplementation may be beneficial to treat fatigue in individuals with iron deficiency without anemia.
Clinical Question: What is the effect of intravenous iron supplementation on fatigue in non-anemic patients?
Summary of Key Findings: A search was conducted to determine the effect of IV iron supplementation on fatigue symptoms. Four studies discussing the use of IV iron supplementation and the effect on fatigue were included. Three studies demonstrated that IV iron supplementation decreased fatigue in iron deficient individuals without anemia. One study demonstrated that there was no effect on fatigue utilizing IV methods of supplementation.
Clinical Bottom Line: The evidence suggests that there is moderate support for the use of IV iron supplementation to treat symptoms of fatigue in individuals with iron deficiency without anemia.
Strength of Recommendation: Based on the PEDro scale and JBI checklist, all of the articles should be included in this critically appraised topic.
Clinical Question: What is the effect of intravenous iron supplementation on fatigue in non-anemic patients?
Summary of Key Findings: A search was conducted to determine the effect of IV iron supplementation on fatigue symptoms. Four studies discussing the use of IV iron supplementation and the effect on fatigue were included. Three studies demonstrated that IV iron supplementation decreased fatigue in iron deficient individuals without anemia. One study demonstrated that there was no effect on fatigue utilizing IV methods of supplementation.
Clinical Bottom Line: The evidence suggests that there is moderate support for the use of IV iron supplementation to treat symptoms of fatigue in individuals with iron deficiency without anemia.
Strength of Recommendation: Based on the PEDro scale and JBI checklist, all of the articles should be included in this critically appraised topic.
| Original language | American English |
|---|---|
| State | Published - 14 Feb 2025 |
| Event | Oklahoma State University Center for Health Sciences Research Week 2025 - Oklahoma State University Center for Health Sciences, Tulsa, United States Duration: 10 Feb 2025 → 14 Feb 2025 https://medicine.okstate.edu/research/research_days.html |
Conference
| Conference | Oklahoma State University Center for Health Sciences Research Week 2025 |
|---|---|
| Country/Territory | United States |
| City | Tulsa |
| Period | 10/02/25 → 14/02/25 |
| Internet address |
Keywords
- iron
- fatigue
- intravenous
- supplementation