Effect of Nutrition and Body Composition on Bone Density After Liver Transplantation

K. M. Khan, S. Mulia, R. Kaul, S. Raatz

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We investigated the relationship between nutrition, body composition, and bone mineral density (BMD) in young adults after liver transplantation. Method: A cross-sectional study involving bone densitometry, anthropometry, and detailed food and lifestyle questionnaires. Results: Of 37 patients recruited, 26 were male. The mean age was 38.8 (±12.3) years, and the posttransplant period was 7.5 (±5.1) years (range 1.3-16.4). A significant proportion of patients (23 [62%]) were overweight (BMI 25-29.9) or obese (BMI ≥30). A total of 20 (54%) patients were osteopenic, and four (11%) had osteoporosis (lumbar spine or total body BMD). Lean mass showed a statistically significant correlation with lumbar spine and total body BMD in men and women, the most significant being bone mineral content, r = 0.66, P = .01. The correlation was stronger in females (r = 0.81, P < .01) than in males (r = 0.56, P < .01). The average daily intake of vitamin D, total protein, and phosphorus was greater than 100% of the American Dietary Reference recommendations, calcium was 90%, and magnesium 56%. There was no significant relationship between any nutritional parameter and BMD nor history of fractures, steroid use, or length of time from transplantation. Conclusion: Osteopenia determined by lumbar spine BMD underestimates poor BMD in our population of young adults after liver transplant. Maintaining muscle mass may be helpful in preserving BMD. The effect of a limited intake of magnesium needs further investigation.

Original languageEnglish
Pages (from-to)3292-3294
Number of pages3
JournalTransplantation Proceedings
Volume39
Issue number10
DOIs
StatePublished - 1 Dec 2007

Fingerprint

Body Composition
Liver Transplantation
Bone Density
Spine
Magnesium
Young Adult
Anthropometry
Densitometry
Metabolic Bone Diseases
Vitamin D
Phosphorus
Osteoporosis
Life Style
Cross-Sectional Studies
Transplantation
Steroids
Calcium
Transplants
Bone and Bones
Food

Cite this

Khan, K. M. ; Mulia, S. ; Kaul, R. ; Raatz, S. / Effect of Nutrition and Body Composition on Bone Density After Liver Transplantation. In: Transplantation Proceedings. 2007 ; Vol. 39, No. 10. pp. 3292-3294.
@article{a24301f291494dcb8cd117d26b1c51e6,
title = "Effect of Nutrition and Body Composition on Bone Density After Liver Transplantation",
abstract = "We investigated the relationship between nutrition, body composition, and bone mineral density (BMD) in young adults after liver transplantation. Method: A cross-sectional study involving bone densitometry, anthropometry, and detailed food and lifestyle questionnaires. Results: Of 37 patients recruited, 26 were male. The mean age was 38.8 (±12.3) years, and the posttransplant period was 7.5 (±5.1) years (range 1.3-16.4). A significant proportion of patients (23 [62{\%}]) were overweight (BMI 25-29.9) or obese (BMI ≥30). A total of 20 (54{\%}) patients were osteopenic, and four (11{\%}) had osteoporosis (lumbar spine or total body BMD). Lean mass showed a statistically significant correlation with lumbar spine and total body BMD in men and women, the most significant being bone mineral content, r = 0.66, P = .01. The correlation was stronger in females (r = 0.81, P < .01) than in males (r = 0.56, P < .01). The average daily intake of vitamin D, total protein, and phosphorus was greater than 100{\%} of the American Dietary Reference recommendations, calcium was 90{\%}, and magnesium 56{\%}. There was no significant relationship between any nutritional parameter and BMD nor history of fractures, steroid use, or length of time from transplantation. Conclusion: Osteopenia determined by lumbar spine BMD underestimates poor BMD in our population of young adults after liver transplant. Maintaining muscle mass may be helpful in preserving BMD. The effect of a limited intake of magnesium needs further investigation.",
author = "Khan, {K. M.} and S. Mulia and R. Kaul and S. Raatz",
year = "2007",
month = "12",
day = "1",
doi = "10.1016/j.transproceed.2007.07.090",
language = "English",
volume = "39",
pages = "3292--3294",
journal = "Transplantation Proceedings",
issn = "0041-1345",
publisher = "Elsevier USA",
number = "10",

}

Effect of Nutrition and Body Composition on Bone Density After Liver Transplantation. / Khan, K. M.; Mulia, S.; Kaul, R.; Raatz, S.

In: Transplantation Proceedings, Vol. 39, No. 10, 01.12.2007, p. 3292-3294.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effect of Nutrition and Body Composition on Bone Density After Liver Transplantation

AU - Khan, K. M.

AU - Mulia, S.

AU - Kaul, R.

AU - Raatz, S.

PY - 2007/12/1

Y1 - 2007/12/1

N2 - We investigated the relationship between nutrition, body composition, and bone mineral density (BMD) in young adults after liver transplantation. Method: A cross-sectional study involving bone densitometry, anthropometry, and detailed food and lifestyle questionnaires. Results: Of 37 patients recruited, 26 were male. The mean age was 38.8 (±12.3) years, and the posttransplant period was 7.5 (±5.1) years (range 1.3-16.4). A significant proportion of patients (23 [62%]) were overweight (BMI 25-29.9) or obese (BMI ≥30). A total of 20 (54%) patients were osteopenic, and four (11%) had osteoporosis (lumbar spine or total body BMD). Lean mass showed a statistically significant correlation with lumbar spine and total body BMD in men and women, the most significant being bone mineral content, r = 0.66, P = .01. The correlation was stronger in females (r = 0.81, P < .01) than in males (r = 0.56, P < .01). The average daily intake of vitamin D, total protein, and phosphorus was greater than 100% of the American Dietary Reference recommendations, calcium was 90%, and magnesium 56%. There was no significant relationship between any nutritional parameter and BMD nor history of fractures, steroid use, or length of time from transplantation. Conclusion: Osteopenia determined by lumbar spine BMD underestimates poor BMD in our population of young adults after liver transplant. Maintaining muscle mass may be helpful in preserving BMD. The effect of a limited intake of magnesium needs further investigation.

AB - We investigated the relationship between nutrition, body composition, and bone mineral density (BMD) in young adults after liver transplantation. Method: A cross-sectional study involving bone densitometry, anthropometry, and detailed food and lifestyle questionnaires. Results: Of 37 patients recruited, 26 were male. The mean age was 38.8 (±12.3) years, and the posttransplant period was 7.5 (±5.1) years (range 1.3-16.4). A significant proportion of patients (23 [62%]) were overweight (BMI 25-29.9) or obese (BMI ≥30). A total of 20 (54%) patients were osteopenic, and four (11%) had osteoporosis (lumbar spine or total body BMD). Lean mass showed a statistically significant correlation with lumbar spine and total body BMD in men and women, the most significant being bone mineral content, r = 0.66, P = .01. The correlation was stronger in females (r = 0.81, P < .01) than in males (r = 0.56, P < .01). The average daily intake of vitamin D, total protein, and phosphorus was greater than 100% of the American Dietary Reference recommendations, calcium was 90%, and magnesium 56%. There was no significant relationship between any nutritional parameter and BMD nor history of fractures, steroid use, or length of time from transplantation. Conclusion: Osteopenia determined by lumbar spine BMD underestimates poor BMD in our population of young adults after liver transplant. Maintaining muscle mass may be helpful in preserving BMD. The effect of a limited intake of magnesium needs further investigation.

UR - http://www.scopus.com/inward/record.url?scp=37049030387&partnerID=8YFLogxK

U2 - 10.1016/j.transproceed.2007.07.090

DO - 10.1016/j.transproceed.2007.07.090

M3 - Article

C2 - 18089374

AN - SCOPUS:37049030387

VL - 39

SP - 3292

EP - 3294

JO - Transplantation Proceedings

JF - Transplantation Proceedings

SN - 0041-1345

IS - 10

ER -