Dr fimbriae coding region associated hemolytic activity of Escherichia coli

Pawel Goluszko; Stella Nowicki; Anil Kaul; Tuan Pham; Bogdan J. Nowicki

doi:10.1016/0378-1097(95)00177-7

Dr fimbriae coding region associated hemolytic activity of Escherichia coli

Pawel Goluszko, Stella Nowicki, Anil Kaul, Tuan Pham, Bogdan J. Nowicki

School of Health Care Administration

Research output: Contribution to journal › Article › peer-review

Abstract

We investigated the hemolytic activity of Escherichia coli strain EC901 carrying plasmid pBJN406 containing genes draA-E involved in expression of the mannose-resistant Dr hemagglutinin, and in its isogenic insertion mutants devised with Tn5, Tn3, and TnphoA. While E. coli BN406 displayed rapid hemolytic activity against equine erythrocytes, insertion mutations in draD and draE, but not in draA, draB, and draC, abolished all hemolytic activity. These data suggest a role for draD and draE in the expression of hemolysis.

Original language	English
Pages (from-to)	13-17
Number of pages	5
Journal	FEMS Microbiology Letters
Volume	130
Issue number	1
DOIs	https://doi.org/10.1016/0378-1097(95)00177-7
State	Published - 15 Jul 1995

Keywords

Dr fimbriae
Escherichia coli
Hemolysis

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10.1016/0378-1097(95)00177-7

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abstract = "We investigated the hemolytic activity of Escherichia coli strain EC901 carrying plasmid pBJN406 containing genes draA-E involved in expression of the mannose-resistant Dr hemagglutinin, and in its isogenic insertion mutants devised with Tn5, Tn3, and TnphoA. While E. coli BN406 displayed rapid hemolytic activity against equine erythrocytes, insertion mutations in draD and draE, but not in draA, draB, and draC, abolished all hemolytic activity. These data suggest a role for draD and draE in the expression of hemolysis.",

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author = "Pawel Goluszko and Stella Nowicki and Anil Kaul and Tuan Pham and Nowicki, {Bogdan J.}",

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AU - Goluszko, Pawel

AU - Nowicki, Stella

AU - Kaul, Anil

AU - Pham, Tuan

AU - Nowicki, Bogdan J.

PY - 1995/7/15

Y1 - 1995/7/15

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AB - We investigated the hemolytic activity of Escherichia coli strain EC901 carrying plasmid pBJN406 containing genes draA-E involved in expression of the mannose-resistant Dr hemagglutinin, and in its isogenic insertion mutants devised with Tn5, Tn3, and TnphoA. While E. coli BN406 displayed rapid hemolytic activity against equine erythrocytes, insertion mutations in draD and draE, but not in draA, draB, and draC, abolished all hemolytic activity. These data suggest a role for draD and draE in the expression of hemolysis.

KW - Dr fimbriae

KW - Escherichia coli

KW - Hemolysis

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Dr fimbriae coding region associated hemolytic activity of Escherichia coli

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Keywords

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