Abstract
Background: Health inequity exists across the scientific and medical community, specifically in the development and design of clinical trials. There is a lack of diversity and representation of historically marginalized groups in the current landscape of clinical research, and our primary objective for this study was to evaluate recruitment and retention strategies for historically marginalized patients in asthma clinical trials.
Methods: We performed a search of major databases — MEDLINE and Embase — to identify clinical trials that performed various interventions and treatment modalities for asthma. Screening and data extraction were performed in a masked and duplicate fashion to limit error. General study characteristics along with recruitment and retention strategies were recorded.
Results: 121 clinical trials were included in our study. Of the included studies, only forty-two (42/121, 34.7%) reported the use of retention and recruitment strategies. Only eighteen (18/121, 14.9%) articles explicitly stated their diversity goals for the participants.
Conclusions: Although many studies reported the use of recruitment strategies, overall the implementation and standardization of these strategies were not adequate. Standardization of recruitment and retention methodologies combined with well-defined recruitment objectives is necessary to improve diversity, equity, and inclusion in clinical trials.
Methods: We performed a search of major databases — MEDLINE and Embase — to identify clinical trials that performed various interventions and treatment modalities for asthma. Screening and data extraction were performed in a masked and duplicate fashion to limit error. General study characteristics along with recruitment and retention strategies were recorded.
Results: 121 clinical trials were included in our study. Of the included studies, only forty-two (42/121, 34.7%) reported the use of retention and recruitment strategies. Only eighteen (18/121, 14.9%) articles explicitly stated their diversity goals for the participants.
Conclusions: Although many studies reported the use of recruitment strategies, overall the implementation and standardization of these strategies were not adequate. Standardization of recruitment and retention methodologies combined with well-defined recruitment objectives is necessary to improve diversity, equity, and inclusion in clinical trials.
| Original language | American English |
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| State | Published - 19 Jul 2024 |
| Event | 8th Biomedical-Neuroscience-Physiology Research Joint Meeting - Tandy 4th Floor Conference Center, Oklahoma State University Center for Health Sciences , 1111 W. 17th Street , Tulsa, United States Duration: 19 Jul 2024 → 19 Jul 2024 |
Conference
| Conference | 8th Biomedical-Neuroscience-Physiology Research Joint Meeting |
|---|---|
| Abbreviated title | Annual Joint Research Meeting |
| Country/Territory | United States |
| City | Tulsa |
| Period | 19/07/24 → 19/07/24 |