Direct Synthesis of Chiral 3-Arylsuccinimides by Rhodium-Catalyzed Enantioselective Conjugate Addition of Arylboronic Acids to Maleimides

Keyphrases

• Rhodium Catalysis 100%
• Arylboronic Acids 100%
• Maleimide 100%
• Enantioselective Conjugate Addition 100%
• Direct Synthesis 100%
• Enantioselectivity 66%
• Bicyclol 66%
• Diene Ligands 66%
• Pyrrolidine 66%
• N-substituted Maleimide 66%
• In Situ 33%
• Cleavable 33%
• Rhodium 33%
• Conjugate Addition 33%
• Synthetic Intermediate 33%
• 1,4-addition Reactions 33%
• Diaryl 33%
• Biologically Active Substances 33%
• Chiral rhodium Catalyst 33%
• N-protecting Groups 33%
• Enantioenriched 33%

Chemistry

• Rhodium 100%
• Pyrrolidine 66%
• Addition Reaction 33%
• Protecting Groups 33%