Dietary fruits and arthritis

Arpita Basu, Jace Schell, R. Hal Scofield

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Arthritis is a global health concern affecting a significant proportion of the population and associated with reduced quality of life. Among the different forms of arthritis, osteoarthritis (OA) and rheumatoid arthritis (RA) are the most common and lacking a definite cure in the affected individuals. Fruits, such as berries and pomegranates are rich sources of a variety of dietary bioactive compounds, especially the polyphenolic flavonoids that have been associated with antioxidant, anti-inflammatory and analgesic effects. Emerging research demonstrates a protective role of fruits and their polyphenols in pre-clinical, clinical and epidemiological studies of OA and RA. In this context, commonly available fruits, such as blueberries, raspberries and strawberries, and pomegranates have shown promising results in reducing pain and inflammation in experimental models and in human clinical studies of arthritis. There is also some evidence on the role of specific fruit polyphenols, such as quercetin and citrus flavonoids in alleviating RA symptoms. These emerging data deserve further investigation in rigorous scientific studies to determine the mechanisms, dosing and selection of fruits and fruit extracts in arthritis management.

Original languageEnglish
Pages (from-to)70-77
Number of pages8
JournalFood and Function
Volume9
Issue number1
DOIs
StatePublished - 1 Jan 2018
Externally publishedYes

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arthritis
Arthritis
Fruit
rheumatoid arthritis
fruits
pomegranates
polyphenols
osteoarthritis
Rheumatoid Arthritis
clinical trials
flavonoids
Polyphenols
Flavonoids
Osteoarthritis
fruit extracts
analgesic effect
raspberries
blueberries
Blueberry Plants
anti-inflammatory activity

Cite this

Basu, Arpita ; Schell, Jace ; Scofield, R. Hal. / Dietary fruits and arthritis. In: Food and Function. 2018 ; Vol. 9, No. 1. pp. 70-77.
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Basu, A, Schell, J & Scofield, RH 2018, 'Dietary fruits and arthritis', Food and Function, vol. 9, no. 1, pp. 70-77. https://doi.org/10.1039/c7fo01435j

Dietary fruits and arthritis. / Basu, Arpita; Schell, Jace; Scofield, R. Hal.

In: Food and Function, Vol. 9, No. 1, 01.01.2018, p. 70-77.

Research output: Contribution to journalArticle

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