Depressive symptoms are associated with obesity in adults with heart failure: An analysis of gender differences

Misty A.W. Hawkins, Carly M. Goldstein, Mary A. Dolansky, John Gunstad, Joseph D. Redle, Richard Josephson, Joel W. Hughes

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: Depression is a predictor and consequence of obesity in the general population. Up to 50% of patients with heart failure exhibit elevated depressive symptoms or depressive disorders; however, research on the depression-obesity relationship in heart failure populations is limited, especially in regard to gender differences. Aims: To conduct total-sample and gender-stratified analyses to determine whether depressive symptoms are associated with body mass index (BMI) in a sample of patients with heart failure. Method: Participants were 348 (39% female, 26% non-White) patients with heart failure (aged 68.7±9.7 years) recruited from urban medical centers. Depressive symptoms were measured using the Patient Health Questionnaire-9 (PHQ-9). Height and weight were used to compute BMI (kg/m2). Regressions were performed for total sample and both genders. Regressions for BMI were run with demographic, medical, and psychological covariates in Step 1 and the PHQ-9 in Step 2. Results: Regression results (total sample) revealed that the PHQ-9 was associated with BMI after adjusting for covariates (β=.22, p=.004). For males, the relationship between PHQ-9 and BMI remained (β=.23, p=.024) and was driven by those with severe obesity (BMI ≥ 40 kg/m2). A trend between PHQ-9 and BMI was detected among females (β=.19, p=.091). Conclusion: BMI is related to depressive symptoms in adults with heart failure even after adjusting for demographic and medical covariates. Depressive symptoms were associated with BMI in males, whereas a trend was detected among females. These findings could ultimately be used to improve heart failure outcomes for depressed, obese individuals with heart failure.

Original languageEnglish
Pages (from-to)516-524
Number of pages9
JournalEuropean Journal of Cardiovascular Nursing
Volume14
Issue number6
DOIs
StatePublished - 1 Dec 2015
Externally publishedYes

Fingerprint

Body Mass Index
Heart Failure
Obesity
Depression
Health
Demography
Morbid Obesity
Depressive Disorder
Population
Surveys and Questionnaires
Psychology
Weights and Measures
Research

Keywords

  • Body mass index
  • depressive symptoms
  • gender
  • heart failure
  • obesity

Cite this

Hawkins, Misty A.W. ; Goldstein, Carly M. ; Dolansky, Mary A. ; Gunstad, John ; Redle, Joseph D. ; Josephson, Richard ; Hughes, Joel W. / Depressive symptoms are associated with obesity in adults with heart failure : An analysis of gender differences. In: European Journal of Cardiovascular Nursing. 2015 ; Vol. 14, No. 6. pp. 516-524.
@article{964521a27f144734b6a6e6c6fe8767d4,
title = "Depressive symptoms are associated with obesity in adults with heart failure: An analysis of gender differences",
abstract = "Background: Depression is a predictor and consequence of obesity in the general population. Up to 50{\%} of patients with heart failure exhibit elevated depressive symptoms or depressive disorders; however, research on the depression-obesity relationship in heart failure populations is limited, especially in regard to gender differences. Aims: To conduct total-sample and gender-stratified analyses to determine whether depressive symptoms are associated with body mass index (BMI) in a sample of patients with heart failure. Method: Participants were 348 (39{\%} female, 26{\%} non-White) patients with heart failure (aged 68.7±9.7 years) recruited from urban medical centers. Depressive symptoms were measured using the Patient Health Questionnaire-9 (PHQ-9). Height and weight were used to compute BMI (kg/m2). Regressions were performed for total sample and both genders. Regressions for BMI were run with demographic, medical, and psychological covariates in Step 1 and the PHQ-9 in Step 2. Results: Regression results (total sample) revealed that the PHQ-9 was associated with BMI after adjusting for covariates (β=.22, p=.004). For males, the relationship between PHQ-9 and BMI remained (β=.23, p=.024) and was driven by those with severe obesity (BMI {\^a}‰¥ 40 kg/m2). A trend between PHQ-9 and BMI was detected among females (β=.19, p=.091). Conclusion: BMI is related to depressive symptoms in adults with heart failure even after adjusting for demographic and medical covariates. Depressive symptoms were associated with BMI in males, whereas a trend was detected among females. These findings could ultimately be used to improve heart failure outcomes for depressed, obese individuals with heart failure.",
keywords = "Body mass index, depressive symptoms, gender, heart failure, obesity",
author = "Hawkins, {Misty A.W.} and Goldstein, {Carly M.} and Dolansky, {Mary A.} and John Gunstad and Redle, {Joseph D.} and Richard Josephson and Hughes, {Joel W.}",
year = "2015",
month = "12",
day = "1",
doi = "10.1177/1474515114542558",
language = "English",
volume = "14",
pages = "516--524",
journal = "European Journal of Cardiovascular Nursing",
issn = "1474-5151",
publisher = "SAGE Publications Inc.",
number = "6",

}

Depressive symptoms are associated with obesity in adults with heart failure : An analysis of gender differences. / Hawkins, Misty A.W.; Goldstein, Carly M.; Dolansky, Mary A.; Gunstad, John; Redle, Joseph D.; Josephson, Richard; Hughes, Joel W.

In: European Journal of Cardiovascular Nursing, Vol. 14, No. 6, 01.12.2015, p. 516-524.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Depressive symptoms are associated with obesity in adults with heart failure

T2 - An analysis of gender differences

AU - Hawkins, Misty A.W.

AU - Goldstein, Carly M.

AU - Dolansky, Mary A.

AU - Gunstad, John

AU - Redle, Joseph D.

AU - Josephson, Richard

AU - Hughes, Joel W.

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Background: Depression is a predictor and consequence of obesity in the general population. Up to 50% of patients with heart failure exhibit elevated depressive symptoms or depressive disorders; however, research on the depression-obesity relationship in heart failure populations is limited, especially in regard to gender differences. Aims: To conduct total-sample and gender-stratified analyses to determine whether depressive symptoms are associated with body mass index (BMI) in a sample of patients with heart failure. Method: Participants were 348 (39% female, 26% non-White) patients with heart failure (aged 68.7±9.7 years) recruited from urban medical centers. Depressive symptoms were measured using the Patient Health Questionnaire-9 (PHQ-9). Height and weight were used to compute BMI (kg/m2). Regressions were performed for total sample and both genders. Regressions for BMI were run with demographic, medical, and psychological covariates in Step 1 and the PHQ-9 in Step 2. Results: Regression results (total sample) revealed that the PHQ-9 was associated with BMI after adjusting for covariates (β=.22, p=.004). For males, the relationship between PHQ-9 and BMI remained (β=.23, p=.024) and was driven by those with severe obesity (BMI ≥ 40 kg/m2). A trend between PHQ-9 and BMI was detected among females (β=.19, p=.091). Conclusion: BMI is related to depressive symptoms in adults with heart failure even after adjusting for demographic and medical covariates. Depressive symptoms were associated with BMI in males, whereas a trend was detected among females. These findings could ultimately be used to improve heart failure outcomes for depressed, obese individuals with heart failure.

AB - Background: Depression is a predictor and consequence of obesity in the general population. Up to 50% of patients with heart failure exhibit elevated depressive symptoms or depressive disorders; however, research on the depression-obesity relationship in heart failure populations is limited, especially in regard to gender differences. Aims: To conduct total-sample and gender-stratified analyses to determine whether depressive symptoms are associated with body mass index (BMI) in a sample of patients with heart failure. Method: Participants were 348 (39% female, 26% non-White) patients with heart failure (aged 68.7±9.7 years) recruited from urban medical centers. Depressive symptoms were measured using the Patient Health Questionnaire-9 (PHQ-9). Height and weight were used to compute BMI (kg/m2). Regressions were performed for total sample and both genders. Regressions for BMI were run with demographic, medical, and psychological covariates in Step 1 and the PHQ-9 in Step 2. Results: Regression results (total sample) revealed that the PHQ-9 was associated with BMI after adjusting for covariates (β=.22, p=.004). For males, the relationship between PHQ-9 and BMI remained (β=.23, p=.024) and was driven by those with severe obesity (BMI ≥ 40 kg/m2). A trend between PHQ-9 and BMI was detected among females (β=.19, p=.091). Conclusion: BMI is related to depressive symptoms in adults with heart failure even after adjusting for demographic and medical covariates. Depressive symptoms were associated with BMI in males, whereas a trend was detected among females. These findings could ultimately be used to improve heart failure outcomes for depressed, obese individuals with heart failure.

KW - Body mass index

KW - depressive symptoms

KW - gender

KW - heart failure

KW - obesity

UR - http://www.scopus.com/inward/record.url?scp=84947064064&partnerID=8YFLogxK

U2 - 10.1177/1474515114542558

DO - 10.1177/1474515114542558

M3 - Article

C2 - 25031311

AN - SCOPUS:84947064064

VL - 14

SP - 516

EP - 524

JO - European Journal of Cardiovascular Nursing

JF - European Journal of Cardiovascular Nursing

SN - 1474-5151

IS - 6

ER -