Cutaneous reactions with tenofovir disoproxil fumarate: A report of nine cases

Staci M. Lockhart, R. Chris Rathbun, Johnny R. Stephens, Damon L. Baker, Douglas A. Drevets, Ronald A. Greenfield, Michelle R. Salvaggio, Simi Vincent

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Abstract

Adverse drug reactions causing the early discontinuation of therapy are common in patients with HIV infection. Hypersensitivity consisting mainly of a maculopapular rash on the face, extremities and trunk has been observed at a rate higher than expected in patients treated with tenofovir at our clinics. We therefore examined nine patients with suspected tenofovir hypersensitivity reactions in two indigent care HIV clinics. Type I and type IV hypersensitivity may be involved as immunological mechanisms.

Original languageEnglish
Pages (from-to)1370-1373
Number of pages4
JournalAIDS
Volume21
Issue number10
DOIs
Publication statusPublished - 1 Jun 2007

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Lockhart, S. M., Rathbun, R. C., Stephens, J. R., Baker, D. L., Drevets, D. A., Greenfield, R. A., ... Vincent, S. (2007). Cutaneous reactions with tenofovir disoproxil fumarate: A report of nine cases. AIDS, 21(10), 1370-1373. https://doi.org/10.1097/QAD.0b013e32811ebf9e