@article{12ac05539a4f498ba584c89e0d17a0f2,
title = "Correspondence Between Perceived Pubertal Development and Hormone Levels in 9-10 Year-Olds From the Adolescent Brain Cognitive Development Study",
abstract = "Aim: To examine individual variability between perceived physical features and hormones of pubertal maturation in 9–10-year-old children as a function of sociodemographic characteristics. Methods: Cross-sectional metrics of puberty were utilized from the baseline assessment of the Adolescent Brain Cognitive Development (ABCD) Study—a multi-site sample of 9–10 year-olds (n = 11,875)—and included perceived physical features via the pubertal development scale (PDS) and child salivary hormone levels (dehydroepiandrosterone and testosterone in all, and estradiol in females). Multi-level models examined the relationships among sociodemographic measures, physical features, and hormone levels. A group factor analysis (GFA) was implemented to extract latent variables of pubertal maturation that integrated both measures of perceived physical features and hormone levels. Results: PDS summary scores indicated more males (70\%) than females (31\%) were prepubertal. Perceived physical features and hormone levels were significantly associated with child{\textquoteright}s weight status and income, such that more mature scores were observed among children that were overweight/obese or from households with low-income. Results from the GFA identified two latent factors that described individual differences in pubertal maturation among both females and males, with factor 1 driven by higher hormone levels, and factor 2 driven by perceived physical maturation. The correspondence between latent factor 1 scores (hormones) and latent factor 2 scores (perceived physical maturation) revealed synchronous and asynchronous relationships between hormones and concomitant physical features in this large young adolescent sample. Conclusions: Sociodemographic measures were associated with both objective hormone and self-report physical measures of pubertal maturation in a large, diverse sample of 9–10 year-olds. The latent variables of pubertal maturation described a complex interplay between perceived physical changes and hormone levels that hallmark sexual maturation, which future studies can examine in relation to trajectories of brain maturation, risk/resilience to substance use, and other mental health outcomes.",
keywords = "adolescent brain cognitive development, dehydroepiandrosterone, estradiol, pubertal development scale, puberty, salivary hormones, testosterone",
author = "Herting, \{Megan M.\} and Uban, \{Kristina A.\} and Gonzalez, \{Marybel Robledo\} and Baker, \{Fiona C.\} and Kan, \{Eric C.\} and Thompson, \{Wesley K.\} and Granger, \{Douglas A.\} and Albaugh, \{Matthew D.\} and Anokhin, \{Andrey P.\} and Bagot, \{Kara S.\} and Banich, \{Marie T.\} and Barch, \{Deanna M.\} and Arielle Baskin-Sommers and Breslin, \{Florence J.\} and Casey, \{B. J.\} and Bader Chaarani and Linda Chang and Clark, \{Duncan B.\} and Cloak, \{Christine C.\} and Constable, \{R. Todd\} and Cottler, \{Linda B.\} and Dagher, \{Rada K.\} and Mirella Dapretto and Dick, \{Anthony S.\} and Nico Dosenbach and Dowling, \{Gayathri J.\} and Dumas, \{Julie A.\} and Sarah Edwards and Thomas Ernst and Fair, \{Damien A.\} and Feldstein-Ewing, \{Sarah W.\} and Freedman, \{Edward G.\} and Fuemmeler, \{Bernard F.\} and Hugh Garavan and Gee, \{Dylan G.\} and Giedd, \{Jay N.\} and Glaser, \{Paul E.A.\} and Aimee Goldstone and Gray, \{Kevin M.\} and Hawes, \{Samuel W.\} and Heath, \{Andrew C.\} and Heitzeg, \{Mary M.\} and Hewitt, \{John K.\} and Heyser, \{Charles J.\} and Hoffman, \{Elizabeth A.\} and Huber, \{Rebekah S.\} and Huestis, \{Marilyn A.\} and Hyde, \{Luke W.\} and Infante, \{M. Alejandra\} and Ivanova, \{Masha Y.\} and Joanna Jacobus and Jernigan, \{Terry L.\} and Karcher, \{Nicole R.\} and Laird, \{Angela R.\} and LeBlanc, \{Kimberly H.\} and Krista Lisdahl and Monica Luciana and Beatriz Luna and Maes, \{Hermine H.\} and Marshall, \{Andrew T.\} and Mason, \{Michael J.\} and McGlade, \{Erin C.\} and Morris, \{Amanda S.\} and Nagel, \{Bonnie J.\} and Neigh, \{Gretchen N.\} and Palmer, \{Clare E.\} and Paulus, \{Martin P.\} and Potter, \{Alexandra S.\} and Puttler, \{Leon I.\} and Nishadi Rajapakse and Kristina Rapuano and Gloria Reeves and Renshaw, \{Perry F.\} and Claudiu Schirda and Sher, \{Kenneth J.\} and Chandni Sheth and Shilling, \{Paul D.\} and Squeglia, \{Lindsay M.\} and Sutherland, \{Matthew T.\} and Tapert, \{Susan F.\} and Tomko, \{Rachel L.\} and Deborah Yurgelun-Todd and Wade, \{Natasha E.\} and Weiss, \{Susan R.B.\} and Zucker, \{Robert A.\} and Sowell, \{Elizabeth R.\}",
note = "Publisher Copyright: {\textcopyright} Copyright {\textcopyright} 2021 Herting, Uban, Gonzalez, Baker, Kan, Thompson, Granger, Albaugh, Anokhin, Bagot, Banich, Barch, Baskin-Sommers, Breslin, Casey, Chaarani, Chang, Clark, Cloak, Constable, Cottler, Dagher, Dapretto, Dick, Dosenbach, Dowling, Dumas, Edwards, Ernst, Fair, Feldstein-Ewing, Freedman, Fuemmeler, Garavan, Gee, Giedd, Glaser, Goldstone, Gray, Hawes, Heath, Heitzeg, Hewitt, Heyser, Hoffman, Huber, Huestis, Hyde, Infante, Ivanova, Jacobus, Jernigan, Karcher, Laird, LeBlanc, Lisdahl, Luciana, Luna, Maes, Marshall, Mason, McGlade, Morris, Nagel, Neigh, Palmer, Paulus, Potter, Puttler, Rajapakse, Rapuano, Reeves, Renshaw, Schirda, Sher, Sheth, Shilling, Squeglia, Sutherland, Tapert, Tomko, Yurgelun-Todd, Wade, Weiss, Zucker and Sowell.",
year = "2021",
month = feb,
day = "18",
doi = "10.3389/fendo.2020.549928",
language = "English",
volume = "11",
journal = "Frontiers in Endocrinology",
issn = "1664-2392",
publisher = "Frontiers Media SA",
}