TY - JOUR
T1 - Complementation of a Clostridium perfringens spo0A mutant with wild-type spo0A from other Clostridium species
AU - Huang, I. Hsiu
AU - Sarker, Mahfuzur R.
PY - 2006/9/1
Y1 - 2006/9/1
N2 - To evaluate whether C. perfringens can be used as a model organism for studying the sporulation process in other clostridia, C. perfringens spo0A mutant IH101 was complemented with wild-type spo0A from four different Clostridium species. Wild-type spo0A from C. acetobutylicum or C. tetani, but not from C. botulinum or C. difficile, restored sporulation and enterotoxin production in IH101. The ability of spo0A from C. botulinum or C. difficile to complement the lack of spore formation in IH101 might be due, at least in part, to the low levels of spo0A transcription and Spo0A production.
AB - To evaluate whether C. perfringens can be used as a model organism for studying the sporulation process in other clostridia, C. perfringens spo0A mutant IH101 was complemented with wild-type spo0A from four different Clostridium species. Wild-type spo0A from C. acetobutylicum or C. tetani, but not from C. botulinum or C. difficile, restored sporulation and enterotoxin production in IH101. The ability of spo0A from C. botulinum or C. difficile to complement the lack of spore formation in IH101 might be due, at least in part, to the low levels of spo0A transcription and Spo0A production.
UR - http://www.scopus.com/inward/record.url?scp=33748798701&partnerID=8YFLogxK
U2 - 10.1128/AEM.02218-05
DO - 10.1128/AEM.02218-05
M3 - Article
C2 - 16957268
AN - SCOPUS:33748798701
SN - 0099-2240
VL - 72
SP - 6388
EP - 6393
JO - Applied and Environmental Microbiology
JF - Applied and Environmental Microbiology
IS - 9
ER -